Medication Safety Reports in Intensive Care Units: A Prospective Multicentric Study

Benkirane, R; Soulaymani, R.; Madani, Naoufal; Haimeur, C.; Kettani, S E Ech Cherif El; Azzouzi, Abderrahim A.; Alaoui, Amal Mrani; Nejmi, M N; Maazouzi, Wajdi

doi:10.2165/00002018-200730100-00021

Cited by 1 publication

(3 citation statements)

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“…In some previous studies of medication errors in ICU, some data on HAM have been reported. Benkirane et al [5] prospectively evaluated the prevalence rate of adverse drug event on 7 adult and pediatric ICUs during 3 months. They report an incidence rate of adverse drug events of 11.5%, mainly due to prescribing errors.…”

Section: Discussionmentioning

confidence: 99%

“…Garrouste-Orgeas et al [7] describes than 95% of anticoagulant prescription and administration errors, and 83% of those related to insulin administration, had no consequence to the patient. Benkirane et al [5] reported than 4% of medication errors related with insulin, 6% of those related with anesthetics (lidocaine and bupivacaine), 0.4% of those related to cardiovascular (diuretics), 0.27% of the related to anticoagulant and 0.2% of those related to sedation/analgesic were serious (seriousness was de ned as a ME that results in death or is life threatening, or requires inpatient hospitalization or prolongation of existing hospitalization or results in persistent or signi cant disability/incapacity).…”

Section: Discussionmentioning

confidence: 99%

“…Also, critical patients in ICU are more vulnerable to medications errors due to the high frequent occurrence of organ dysfunctions (mainly deranged kidney and liver function) and altered pharmacokinetics and pharmacodynamics of drugs. So, it is estimated an incidence of 1.2 to 967 medications errors per 1000 patients day in ICU [2][3][4][5].…”

Section: Introductionmentioning

confidence: 99%

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High-alert medications errors in a Critical Care Unit

Pintado-Delgado,

Sánchez-Navarro,

Baldominos-Utrilla

2023

Preprint

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Purpose To describe the voluntarily reported medications errors related to high-alert medications (HAM) in an adult Intensive Care Unit (ICU).Methods Retrospective observational study. We reviewed all the ICU medications errors related to HAMs reported to intranet-accessible, anonymous adverse event –reporting program by healthcare professionals over 36 months.Results Of the 268 medication errors reported, 102 (38.0%) were related to HAMs. Insulin (19.6%), followed of adrenergic agonist (15.7%), were the most frequent drug class associated with medication error. Prescription errors (54.0%) were the most frequent type of error, mainly related to the use of verbal orders that were not prescribed. Most of the reported medication error (63.7%) did not result in harm to the patient, being the alterations of plasma glucose levels the most frequent harm. All reported damages were transient and resolved with treatment, but all, of them prolonged the stay in ICU.Conclusion Medications errors related to HAMs in UCI are frequent, up to 38% of all the medications errors notified. In our study, most of them were related to insulin and adrenergic agonist. Although in most cases they are not related to permanent damage or death, in 34.3% of them there is an increase in ICU stay.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%