Medication use and drug-related problems among women at maternity wards—a cross-sectional study from two Norwegian hospitals

Smedberg, Janne; Bråthen, Magne; Waka, M. S.; Jacobsen, Anne Flem; Gjerdalen, G. F.; Nordeng, Hedvig

doi:10.1007/s00228-016-2042-0

Cited by 27 publications

(48 citation statements)

References 42 publications

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“…The role of the pharmacists may be important, since they are often the first health care provider that pregnant women visit to request advice/information, in order to address misconceptions regarding the use of medications. This finding is in concordance with present literature [ 11 , 24 , 26 ].…”

Section: Discussionsupporting

confidence: 94%

Knowledge, attitudes, and practice regarding medication use in pregnant women in Southern Italy

et al. 2018

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The study assessed knowledge, attitudes, and medication use of a random sample of pregnant women attending outpatient Gynecology and Obstetrics clinics at randomly selected public General and Teaching hospitals in Naples, Italy. A total of 503 women participated. Those more likely to know that a pregnant woman with chronic condition must discuss whether or not to take a medication with the physician were Italian, aged 31–40 years, employed, with no history of abortion, having had a medical problem within the previous year, with a better self-perceived health status, who knew how to use medications during pregnancy, and who needed information on medications. The knowledge of the potential risk of using non-prescribed medications during pregnancy was significantly higher in employed women, who received information from physicians, who knew how to use medications during pregnancy, and who knew the possible damages related to medications use. More than half had used at least one medication. Those aged 26–35 years, Italian, non-graduated, in the third trimester, having had a medical problem within the previous year, with a risky pregnancy, and with a knowledge that women with chronic condition must discuss whether or not to take a medication with the physician were more likely to use medication. Less than half had used medication without a physician’s advice. Those who were more likely to self-medicate were older, Italian, multiparous, with no history of abortion, who knew that women with chronic condition must discuss whether or not to take a medication with the physician, who did not know the potential risk of using non-prescribed medication during pregnancy, who had used prescribed medication during pregnancy, and who needed information about medications. Educational programs for women about medication use are important to increase their knowledge of the potential risks to the pregnant women and the unborn child in order to reduce self-medication.

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Section: Discussionsupporting

confidence: 94%

Knowledge, attitudes, and practice regarding medication use in pregnant women in Southern Italy

et al. 2018

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“…In addition, studies in non-pregnant patients have shown the effectiveness of pharmacists' counselling on medication adherence, persistence, clinical management and therapeutic outcomes [16][17][18][19][20][21][22]. This is important since two recent studies have shown medication-related problems (MRP) frequently occur among pregnant women [23,24]. These MRP were largely resolved by pharmacists correcting misperceptions, providing information, and empowering the women to make safe decisions about medication use [23].…”

Section: Introductionmentioning

confidence: 99%

“…This is important since two recent studies have shown medication-related problems (MRP) frequently occur among pregnant women [23,24]. These MRP were largely resolved by pharmacists correcting misperceptions, providing information, and empowering the women to make safe decisions about medication use [23]. The potential contribution of pharmacists to improve fetal-maternal health has been recognized by the International Pharmaceutical Federation (FIP), stating that pharmacists can detect the use of potential teratogenic medicines and counsel pregnant women on alternative medicines [25].…”

Section: Introductionmentioning

confidence: 99%

Women’s Beliefs About Medicines and Adherence to Pharmacotherapy in Pregnancy: Opportunities for Community Pharmacists

Ceulemans

Lupattelli

Nordeng

et al. 2019

CPD

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BackgroundDuring pregnancy women might weigh benefits of treatment against potential risks to the unborn child. However, non-adherence to necessary treatment can adversely affect both mother and child. To optimize pregnant women's beliefs and medication adherence, community pharmacists are ideally positioned to play an important role in primary care. ObjectiveThis narrative review aimed to summarize the evidence on 1) pregnant women's beliefs, 2) medication adherence in pregnancy, and 3) community pharmacists' counselling during pregnancy. MethodThree search strategies were used in Medline and Embase to find original studies evaluating women's beliefs, medication adherence and community pharmacists' counselling during pregnancy. All original descriptive and analytic epidemiological studies performed in Europe, North America and Australia, written in English and published from 2000 onwards were included. ResultsWe included 14 studies reporting on women's beliefs, 11 studies on medication adherence and 9 on community pharmacists' counselling during pregnancy. Women are more reluctant to use medicines during pregnancy and tend to overestimate the teratogenic risk of medicines. Risk perception varies with type of medicine, level of health literacy, education level and occupation. Furthermore, low medication adherence during pregnancy is common. Finally, limited evidence showed current community pharmacists' counselling is insufficient. Barriers hindering pharmacists are insufficient knowledge and limited access to reliable information. ConclusionConcerns about medication use and non-adherence are widespread among pregnant women. Community pharmacists' counselling during pregnancy is insufficient. Further education, training and research are required to support community pharmacists in fulfilling all the opportunities they have when counselling pregnant women.

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“…A medication-related problem (MRP) is de ned as an unwanted event or circumstance involving medication therapy that actually or potentially interferes with desired health outcomes [1,2]. Studies have shown that the prevalence of MRPs among hospitalized pregnant patients varies from 42-83% [3,4].…”

Section: Introductionmentioning

confidence: 99%

Medication-related problems among hospitalized pregnant women in a tertiary teaching hospital in Ethiopia: A prospective observational study

AHMED

Sundby

Aragaw

et al. 2020

Preprint

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Background Studies on medication-related problems (MRPs) among pregnant women are scarce, despite the potential consequences for both mother and child. This study aimed to describe the prevalence, clinical significance, and risk factors for MRPs among hospitalized pregnant or postpartum women at Jimma University Medical Centre (JUMC) in Ethiopia. Methods A prospective follow-up and clinical audit of 1,117 hospitalized pregnant or postpartum women in the maternity and gynaecology wards at JUMC was carried out between February and June 2017. Patients were followed throughout their stay in the hospital to assess the presence and development of MRPs. Pre-tested data extraction form and an interview-guided structured questionnaire were used to collect data. Descriptive statistics were used to describe MRPs. Logistic regression analysis was used to identify factors associated with MRPs. Results One or more MRPs occurred among 323 (28.9%) study participants, mostly in relation to lack of iron supplementation. A total of 278 (70.6%) of all MRPs were considered to be of moderate to high clinical significance. Nulliparous women were more likely to experience MRPs than their counterparts (adjusted OR 1.82; 95% CI 1.23, 2.69). When excluding MRPs due to iron from the analysis, nulliparous women (adjusted OR 1.99; 95% CI 1.22, 3.24) and previous medication use were significantly associated with experiencing an MRP (adjusted OR 2.38; 95% CI 1.24, 4.56). Conclusions Nearly 3 out of 10 hospitalized pregnant women at JUMC had one or more MRPs. The need for additional iron therapy was by far the most common type of MRP. Improved adherence to guidelines on iron supplementation are required. Multidisciplinary approaches including physicians, nurses, and clinical pharmacists in the maternity and gynaecology wards could possibly prevent MRPs and promote patient safety for women and children.

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Medication use and drug-related problems among women at maternity wards—a cross-sectional study from two Norwegian hospitals

Cited by 27 publications

References 42 publications

Knowledge, attitudes, and practice regarding medication use in pregnant women in Southern Italy

Knowledge, attitudes, and practice regarding medication use in pregnant women in Southern Italy

Women’s Beliefs About Medicines and Adherence to Pharmacotherapy in Pregnancy: Opportunities for Community Pharmacists

Medication-related problems among hospitalized pregnant women in a tertiary teaching hospital in Ethiopia: A prospective observational study

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