Medicinal Flowers. XI. Structures of New Dammarane-Type Triterpene Diglycosides with Hydroperoxide Group from Flower Buds of Panax ginseng

Peroxy natural products

“…279,280 The same species contained six dammarane-type triterpene diglycosides, floralginsenosides A-F 470-475, five dammarane triterpene triglycosides, floralginsenosides G-K 476-480, and a dammarane triterpene obligoglycoside, ginsenoside SF 481. [281][282][283] Six dammarane triterpenes, named probosciderols D-I 482-487, have been found in Proboscidea louisiana. 284 The stem bark of Rhus javanica contained a dammarane triterpene designated as isofouquierone peroxide 488.…”

Protection by Panax ginseng C.A. Meyer against the genotoxicity of doxorubicin in somatic cells of Drosophila melanogaster

“…The root of Panax ginseng C. A. Meyer (Araliaceae), a common plant in eastern Asia, is widely used in Chinese natural medicine (Lee et al, 2004;Yoshikawa et al, 2007). Panax ginseng is also being increasingly prescribed in Korea, Japan and Western countries for the treatment of cancer, diabetes, chronic inflammation, and neurodegenerative and cardiovascular diseases (Yun, 1996;Radad et al, 2006).…”

Medicinal Flowers. XXVI. Structures of Acylated Oleanane-Type Triterpene Oligoglycosides, Yuchasaponins A, B, C, and D, from the Flower Buds of <i>Camellia oleifera</i>&mdash;Gastroprotective, Aldose Reductase Inhibitory, and Radical Scavenging Effects&mdash;

“…10,11) Furthermore, those oligoglycosides were found to exhibit antiallergic, 6) antidiabetic, 7) antiobesitic, 5,8) gastroprotective, 7,10,11) and platelet aggregation 10,11) activities. In the course of our characterization studies on Camellia speicies [12][13][14][15] and medicinal flowers, [16][17][18][19][20][21] we found that the methanolic (MeOH) extract and its 1-butanol (1-BuOH)-soluble fraction from the flower buds of C. oleifera showed gastroprotective effects on ethanol-or indomethacin-induced gastric mucosal lesions in rats. The 1-BuOH-and ethyl acetate (EtOAc)-soluble fractions exhibited inhibitory activities on rat lens aldose reductase and scavenging effects on 1,1-diphenylpicryl-2-hydrazyl (DPPH) radical and superoxide.…”