Medicinal plants of Jordan: Scoping review

Abu-Odeh, Ala' M; Fino, Leen; Al-Absi, Ghadeer H.; Alnatour, Dalal; Al-Darraji, Mustafa Nuhad; Shehadeh, Mayadah B.; Suaifan, Ghadeer A. R. Y.

doi:10.1016/j.heliyon.2023.e17081

Cited by 7 publications

(2 citation statements)

References 113 publications

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“…It has analgesic, antipyretic, anti-inflammatory, spasmolytic, and convulsion treatment properties, among others. [12,14] Several studies have demonstrated that Ruta species exhibit various biological activities, such as antioxidant properties, [12,15,16] cytotoxic activity, [12,13,17] anticonvulsant and antinociceptive effects, [18] anti-inflammatory effects, [15] acetyl-cholinesterase inhibition, [16] antimicrobial activity, [19,20] amebicide activity, [21] and antihemolytic activity. [17] In Jordan, there has been limited reporting on the antibacterial and antioxidant properties of R. chalepensis ethanolic extract.…”

Section: Introductionmentioning

confidence: 99%

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Chemical Composition, Antioxidant, and Antibacterial Activity of Ruta chalepensis L. Ethanolic Extract

Althaher,

Oran,

Awadallah

et al. 2024

Chemistry & Biodiversity

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Ruta chalepensis L. is a versatile herb used in culinary arts and traditional medicine. The study aimed to determine the chemical composition of an ethanolic extract from R. chalepensis and the total phenolic and flavonoid content. Additionally, the extracts' antimicrobial and antioxidant activities were tested. The disc diffusion method and minimum inhibitory concentration (MIC) were used to test the antibacterial properties on four types of bacteria: Escherichia coli, Proteus penneri, Bacillus cereus, and Staphylococcus aureus. A colorimetric assay was used to evaluate the total phenolic and flavonoid content, and the DPPH method was used to assess the antioxidant activity. The phytochemical constituents were determined using LC‐MS/MS. The results indicated that R. chalepensis ethanolic extract had 34 compounds, and the predominant compounds were quercetin (9.2%), myricetin (8.8%), and camphene (8.0%). Moreover, the extract had a good level of polyphenols and flavonoids, as demonstrated by inhibiting free radicals (DPPH) (IC50 was 41.2±0.1). Also, the extract exhibited robust antimicrobial activity against P. penneri and S. aureus with an MIC of 12.5 and 25.0 μg/mL, respectively. In conclusion, the results suggest that the R. chalepensis ethanolic extract has good antioxidant and antibacterial properties that could be utilized to develop new antibacterial agents.

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Section: Introductionmentioning

confidence: 99%

“…In addition to its culinary uses, R. chalepensis has numerous health benefits. It has analgesic, antipyretic, anti‐inflammatory, spasmolytic, and convulsion treatment properties, among others [12,14] …”

Section: Introductionmentioning

confidence: 99%