Medicinal use of Cochlospermum tinctorium in Mali

Nergård, Cecilie Sogn; Diallo, Drissa; Inngjerdingen, Kari Tvete; Michaelsen, Terje E.; Matsumoto, Tsukasa; Kiyohara, Hiroaki; Yamada, Hideaki; Paulsen, Berit Smestad

doi:10.1016/j.jep.2004.09.018

Cited by 88 publications

(39 citation statements)

References 57 publications

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“…Other Cochlospermum species, mostly C. tinctorium , have also been investigated. For example, extracts of the root and rhizome of C. tinctorium have been evaluated for cytotoxic, antimicrobial, antiplasmodial, anti-ulcer, antioxidant, hepatoprotective, and immunomodulating effects [8,9,10,11,12]. Preliminary antibacterial and antifungal evaluation was also performed on the ethanolic leaf extract of Brazilian C. regium [13].…”

Section: Introductionmentioning

confidence: 99%

Hydroxybenzoic Acids Are Significant Contributors to the Antioxidant Effect of Borututu Bark, Cochlospermum angolensis Welw. ex Oliv

Abourashed

2017

Antioxidants

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Borututu (Cochlospermum angolensis) is an African tree whose bark has recently emerged as a herbal dietary supplement with claims for antioxidant activity. In order to substantiate the claimed activity of borututu supplements, we performed an activity-guided fractionation of the total extract utilizing a 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radical scavenging assay. Subsequent flash and centrifugal chromatography resulted in the isolation of gallic acid (1) and protocatechuic acid (2) as the main antioxidant constituents. Two apocarotenoids and one flavonoid were also isolated from the chloroform fraction and were identified as cochloxanthin (3), dihydrocochloxanthin (4), and 7,4′-dimethyltaxifolin (5), respectively. A High-performance liquid chromatography (HPLC) method was also developed for fingerprinting borututu samples, with Compounds 1–4 suggested as chemical markers for quality control purposes.

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Section: Introductionmentioning

confidence: 99%

Hydroxybenzoic Acids Are Significant Contributors to the Antioxidant Effect of Borututu Bark, Cochlospermum angolensis Welw. ex Oliv

Abourashed

2017

Antioxidants

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“…Several papers have been published for pharmacological proprieties in medicinal plants or their isolated constituents like antioxidant, antidiabetic, antibacterial, antiviral, and antiulcer activities [1–5]. …”

Section: Introductionmentioning

confidence: 99%

Chemical Composition and, Cellular Evaluation of the Antioxidant Activity of Desmodium adscendens Leaves

Muanda¹,

Bouayed²,

Djılanı³

et al. 2010

Evidence-Based Complementary and Alternative Medicine

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Desmodium adscendens plant is widely used as juice or tea in various parts of the world against a wide range of diseases. This study determines the quality and the quantity of polyphenols, flavonoids, anthocyanins, and tannins in D. adscendens leaves by UV-spectrophotometry and RP-HPLC methods. In addition, the antioxidant capacity of these phenolic compounds is evaluated by ABTS (2,2′-azino-bis(3-ethylbenzothiazoline-6-sulfonic)), DPPH (2,2-diphenyl-1 picrylhydrazyl), and Cellular tests. D. adscendens leaves are mainly composite of flavonoid compounds with 12.8 mg of catechin equivalent (CE)/g dw. The amounts of total polyphenol compounds are 11.1 mg of gallic acid equivalent (GAE)/g dw. The quantity of total anthocyanin and total tannin compounds is not considerable 0.0182 mg CgE/g dw and 0.39 mg CE/g dw, respectively. A direct correlation between phenolic compounds and antioxidant activity is observed (R 2 = 0.96). The RP-HPLC analyses reveal that the main phenolic compound identified in the methanol-water extract is quercetrin dihydrat (2.11 mg/mL). According to the results, it is observed that D. adscendens leaves possess a considerable scavenging antioxidant and antiradical capacity, therefore these antioxidant properties might increase the therapeutic value of this medicinal plant.

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“…This is due to the important role that antioxidants play in protecting the human body from free radicals and retard the progress of many chronic diseases, all negatively affecting the immune system [13,14]. Recently, many studies has been aimed to investigate the radical-scavenging activity of immunomodulating polysaccharides [15][16][17][18][19] or both the immunological and radical-scavenging activities of polysaccharides-and phenolicscontaining extracts and isolated polysaccharides from new plant sources [20][21][22].…”

Section: Introductionmentioning

confidence: 99%

Norway spruce galactoglucomannans exhibiting immunomodulating and radical-scavenging activities

Ebringerová

Hromàdková

Hřı́balová

et al. 2008

International Journal of Biological Macromolecules

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Medicinal use of Cochlospermum tinctorium in Mali

Cited by 88 publications

References 57 publications

Hydroxybenzoic Acids Are Significant Contributors to the Antioxidant Effect of Borututu Bark, Cochlospermum angolensis Welw. ex Oliv

Hydroxybenzoic Acids Are Significant Contributors to the Antioxidant Effect of Borututu Bark, Cochlospermum angolensis Welw. ex Oliv

Chemical Composition and, Cellular Evaluation of the Antioxidant Activity of Desmodium adscendens Leaves

Norway spruce galactoglucomannans exhibiting immunomodulating and radical-scavenging activities

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