Medicinal uses and health benefits of chili pepper (Capsicum spp.): a review

Saleh, Brhan Khiar; Omer, Abdella; Teweldemedhin, Belay

doi:10.15406/mojfpt.2018.06.00183

Cited by 110 publications

(77 citation statements)

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“…In accordance with the World Health Organization, inquiries about its toxicity, safety, potency, value, accessibility, protection, and additional improvement are required. It was revealed that about 4 out of 10 people in the UK employ alternative medicine sometimes in their lives [14]. Therefore, the aim of this work is to focus on the nutritional value, morphology and extraction procedures as well as the therapeutic properties and uses, recommended doses, toxicity, and pharmacokinetics of chili pepper.…”

Section: Introductionmentioning

confidence: 99%

Biological Properties, Bioactive Constituents, and Pharmacokinetics of Some Capsicum spp. and Capsaicinoids

Batiha

Alqahtani

Ojo

et al. 2020

IJMS

160

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Pepper originated from the Capsicum genus, which is recognized as one of the most predominant and globally distributed genera of the Solanaceae family. It is a diverse genus, consisting of more than 31 different species including five domesticated species, Capsicum baccatum, C. annuum, C. pubescen, C. frutescens, and C. chinense. Pepper is the most widely used spice in the world and is highly valued due to its pungency and unique flavor. Pepper is a good source of provitamin A; vitamins E and C; carotenoids; and phenolic compounds such as capsaicinoids, luteolin, and quercetin. All of these compounds are associated with their antioxidant as well as other biological activities. Interestingly, Capsicum fruits have been used as food additives in the treatment of toothache, parasitic infections, coughs, wound healing, sore throat, and rheumatism. Moreover, it possesses antimicrobial, antiseptic, anticancer, counterirritant, appetite stimulator, antioxidant, and immunomodulator activities. Capsaicin and Capsicum creams are accessible in numerous ways and have been utilized in HIV-linked neuropathy and intractable pain.

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Section: Introductionmentioning

confidence: 99%

Biological Properties, Bioactive Constituents, and Pharmacokinetics of Some Capsicum spp. and Capsaicinoids

Batiha

Alqahtani

Ojo

et al. 2020

IJMS

160

View full text Add to dashboard Cite

show abstract

“…High enzyme amount is obtained from Capsicum annuum, which belong to familySolanaceae.Globally pepper is known for its high nutritional value, health benefits and medicinal properties. It is rich in vitamins and minerals, has antimicrobial and anticancer properties (Saleh et al, 2018). The specific activity of crude enzyme in (Capsicum annuum) was 90.51 U/mg (Table 2), while on purification specific activity of 234 U/mg was achieved.…”

Section: Discussionmentioning

confidence: 99%

Purification of Robust L-Asparaginase from Capsicum annum and its Therapeutic Efficacy in Leukemia

Ambreen¹

2019

PVJ

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Medicinal plants used for the treatment of chronic diseases, have attracted the interest of scientists. L-Asparaginase is an extracellular enzyme with biomedical significance. The present article discusses the extraction, purification and characterization of L-asparaginase. Enzyme activity was estimated from Chillies (plant of Solanaceae family). Enzyme titer of 112 U/mL was attained from crude extract of Chillies (Capsicum annum) fruit while purified enzyme after gel filtration provided 61.99% yield, activity of 69.43 U/mL and specific activity of 234 U/mg. L-Asparaginase stability was envisaged at optimal pH of 8.6 in the presence of alkaline buffer. Optimal substrate concentration for L-Asparaginase activity was 200 mMoL. The efficacy of purified enzyme was tracked in vivo model. Normal healthy rats were used as control, which were compared with leukemic rats after treatment with enzyme L-Asparaginase. Eventually after treatment with enzyme extract provided best recovery in leukemic model due to high titer of L-Asparaginase, which bears high antineoplastic activity. It may be employed for chemotherapy in tumors such as acute lymphocytic leukemia.

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“…Chili peppers are rich in many minerals, vitamins, and amino acids essential for human health and growth. Peppers contain a wide array of phytochemicals such as vitamins, phenolics, and flavonoids that have anti-oxidants, antimicrobial and anti-degenerative properties ( Jagtap et al, 2012 , Omolo et al, 2014 , Fattori et al, 2016 , Ganguly et al, 2017 , Saleh et al, 2018 ). The cultivation of Chilli is severely affected by many diseases caused by multiple pathogens including viruses, fungus, bacteria and nematodes.…”

Section: Introductionmentioning

confidence: 99%

Molecular diagnosis of begomovirus associated with Chilli leaf curl disease in Jeddah, Saudi Arabia

Sohrab

2020

Saudi Journal of Biological Sciences

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Chilli ( Capsicum annum L.) is well known as ‘wonder spice’. This is a very valuable cash crop grown as a vegetable globally. Chilli leaf curl disease is a major threat and global concern for the cultivation of Chilli by farmers and growers. In this work, the molecular diagnosis, genetic diversity, phylogenetic relationship, and begomovirus association with Chilli leaf curl disease have been discussed. The infected leaves were randomly harvested from the Chilli field, at Jeddah, Saudi Arabia. A group of begomovirus vector, whiteflies were also observed on the Chilli crop and infected weeds growing in the neighboring field. The begomovirus was confirmed by coat protein gene specific primer, dot blot hybridization, sequencing and sequence analysis. The full coat protein gene was found to have 774 nucleotides. The nucleotide sequences analysis shared the highest identity with Tomato yellow leaf curl virus reported earlier infecting tomato from Saudi Arabia, and the lowest identity was observed with Tomato yellow leaf curl virus Oman isolate. The overall sequence identity ranged from more than ninety percent among the analyzed sequences. The phylogenetic relationship analysis formed the major three clusters and showed the closed clustering with Tomato yellow leaf curl virus isolates. The natural spread of the Tomato yellow leaf curl virus on the Chilli crop from other crops poses an important and serious threat to Chili cultivation in the Kingdom of Saudi Arabia. Based on the literature review and current evidence, this is the first report of leaf curl disease of Chilli from Saudi Arabia.

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Medicinal uses and health benefits of chili pepper (Capsicum spp.): a review

Cited by 110 publications

References 0 publications

Biological Properties, Bioactive Constituents, and Pharmacokinetics of Some Capsicum spp. and Capsaicinoids

Biological Properties, Bioactive Constituents, and Pharmacokinetics of Some Capsicum spp. and Capsaicinoids

Purification of Robust L-Asparaginase from Capsicum annum and its Therapeutic Efficacy in Leukemia

Molecular diagnosis of begomovirus associated with Chilli leaf curl disease in Jeddah, Saudi Arabia

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