Medicinal uses, pharmacology, and phytochemistry of Convolvulaceae plants with central nervous system efficacies: A systematic review

Abstract

Central nervous system (CNS) disorders play a major impact on individual lives and place a severe strain on health care resources. Convolvulaceae is a family comprising approximately 1,600-1,700 species grouped in 55-60 genera, and many species are reported to have an effect on CNS functions. A systematic review of the literature studies was carried out to summarize available evidences on Convolvulaceae plants with CNS efficacies. This review is based on various data sources such as Google Scholar, Web of Science, Scopus, PubMed, and Wanfang Data. A total of 200 related articles were included in this review. According to the research result, 54 Convolvulaceae species are suggested to display CNS efficacies historically, and 46 species have been evaluated for their CNS efficacies. In addition, 67 compounds from 16 Convolvulaceae species are recognized to possess CNS efficacies. Despite great progress made through pharmacology and phytochemistry studies on CNS active Convolvulaceae species, more exploratory research is needed to gain a better understanding of the CNS efficacies of this plant family.

Convolvulus plant—A comprehensive review from phytochemical composition to pharmacy

“…They are found on all continents except for circumpolar areas (Staples, ; Staples & Austin, ; Staples & Noltie, ). Convolvulus (convolere) is a genus of the Convolvulaceae family (bindweed or glory family), which is one of the medicinally and economically important family, including about 250 species of flowering plants, present as trees, shrubs, and herbs (Al‐Snafi, ; Chen, Lu, Yang, Li, & Fan, ; Nacef, Jannet, Abreu, & Mighri, ; Staples, ; Staples & Austin, ; Staples & Noltie, ). The use of the Latin and common name of Convolvulus plants for each species was complicated before the currently accepted names because of the widespread of this family in the world (Al‐Snafi, ; Austin, ).…”

“…Researchers have paid attention to Convolvulus plants and their corresponding extracts and oils because of their important phytochemical composition, bioavailability, clinical effectiveness, and safety (Chen et al, ). Recently, extensive studies conducted on the biological activities of Convolvulus species such as antioxidant effects of the C. prostratus (Singh & Vora, ) and C. pilosellifolius (Al‐Rifai et al, ).…”

Pharmacological evaluation of Convolvulus pluricaulis as hypolipidaemic agent in Triton WR-1339-induced hyperlipidaemia in rats

“…The last few years have witnessed a tremendous escalation in the field of herbal preparations, and these preparations are getting recognition both in developed and in developing countries because of their natural derivation and lesser side effects. About 51% of approved drugs, directly or indirectly belongs to natural origin in the last three decades . Such remedies enjoy the advantage of being from natural origin and having lesser side effects.…”

“…About 51% of approved drugs, directly or indirectly belongs to natural origin in the last three decades. [8] Such remedies enjoy the advantage of being from natural origin and having lesser side effects. These all herbal medicines need to be standardized and compared with existing allopathic medicines.…”

Chronic pelvic pain syndrome: Highlighting medicinal plants toward biomolecules discovery for upcoming drugs formulation

“…Actaea racemosa L., Eschscholzia californica Cham., C. cava, and T. ruticarpum have been shown to be beneficial for this approach (Borrelli & Ernst, 2008;Mils & Bone, 2012). In addition, phytotherapy can also be useful in the treatment of psychological disorders, particularly depression and/or anxiety (Bandelow et al, 2015;Chen, Lu, Yang, Li, & Fan, 2018;Ernst, 2006;Farah et al, 2016;Gomes, Campos, Órfão, & Ribeiro, 2009;Lakhan & Vieira, 2010;Liu et al, 2015; Muszy nska, Łojewski, Rojowski, Opoka, & Sułkowska-Ziaja, 2015; Sarris, 2018;Sarris et al, 2009;Yeung, Hernandez, Mao, Haviland, & Gubili, 2018;Zhang, Zeng, et al, 2017).…”