Medicine–food herb:Angelica sinensis, a potential therapeutic hope for Alzheimer's disease and related complications

Abstract

Alzheimer's disease (AD) is a progressive neurodegenerative disease, which has brought huge burden to the world. Current therapeutic approach of One-molecule-one-target strategy fails to address the issues because of multiple...

Sustainable extraction of ligustilide and ferulic acid from Angelicae Sinensis Radix, for antioxidant and anti-inflammatory activities

“…Accordingly, modern pharmacological studies gradually had realized ASR anti-inflammatory effect [4] such as therapeutic effect for hepatitis [5] and inflammation induced by subcutaneous, carrageenan or lipopolysaccharides (LPS) [6] , [7] . ASR contains a variety of plant active components, mainly including polysaccharides, ferulic acid (FA), amino acids and ligustilide (LIG) and so on [8] . FA (4-hydroxyl-3-methoxy-cinnamic acid) is a kind of phenolic acid, and it has the potential to be utilized in the field of food, pharmaceutical and biomedical industries due to its diverse physiological functions, such as antioxidant, antimicrobial and anti-inflammatory properties.…”

Volatile flavour identification and odour complexity of radix Angelicae sinensis by electronic nose, integrated gas chromatography–mass spectrometry/olfactometry and comprehensive two‐dimensional gas chromatography‐time‐of‐flight‐mass spectrometry

“…8 These phytochemicals have made DG play a vital role in its applications as a health food. 6 Moreover, DG has a wide range of pharmacological utilities, such as anti-inflammation, 9,10 antioxidation, 3,11,12 antibacterial, 13,14 anxiolytics, 15 antitumour, 16 anti-angiogenic, 17 detumescence, 18 and liver protection. 19 Besides in Asian countries, DG has also been exploited as a dietary supplement in women's care in Europe and America.…”

“…Many studies showed that DG herb consists of a large variety of volatile substances, 2 polysaccharides, 3 organic acids, 4 amino acids, 5 vitamins, 6 and microelements, 7 among others 8 . These phytochemicals have made DG play a vital role in its applications as a health food 6 . Moreover, DG has a wide range of pharmacological utilities, such as anti‐inflammation, 9,10 antioxidation, 3,11,12 antibacterial, 13,14 anxiolytics, 15 antitumour, 16 anti‐angiogenic, 17 detumescence, 18 and liver protection 19 .…”

“…Many studies showed that DG herb consists of a large variety of volatile substances, 2 polysaccharides, 3 organic acids, 4 amino acids, 5 vitamins, 6 and microelements, 7 among others. 8 These phytochemicals have made DG play a vital role in its applications as a health food.…”

“…This was primitively described in an ancient, authoritative Chinese medicine classic named the Shennong's Classic of Materia Medica ( ad 200–300, Han Dynasty). Many studies showed that DG herb consists of a large variety of volatile substances, 2 polysaccharides, 3 organic acids, 4 amino acids, 5 vitamins, 6 and microelements, 7 among others 8 . These phytochemicals have made DG play a vital role in its applications as a health food 6 .…”