Medición ecocardiográfica de la grasa epicárdica

Lima-Martínez, Marcos M.; Balladares, Nathalie; Torres, Christopher; Guerra, Ernesto; Contreras, Miguel

doi:10.1016/s2171-3669(11)70023-3

Cited by 8 publications

(2 citation statements)

References 13 publications

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“…For epicardial fat measurement a mode M ultrasound was done with a 3.5 MHz transducer considering the hypoechoic space between the outer wall of the myocardium and the visceral layer of the pericardium in the parasternal longitudinal view and perpendicular to the free wall of the right ventricle perpendicular to the aortic ring at the end of the systole in three cardiac cycles [ 36 ]. It was considered abnormal when ≥ 5 mm [ 37 - 40 ].…”

Section: Methodsmentioning

confidence: 99%

Relationship of the neutrophil/lymphocyte ratio with cardiovascular risk markers in premenopausal and postmenopausal women

Carranza-Lira

Montiel

Camacho

et al. 2020

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Introduction Cardiovascular disease is more frequent in postmenopausal women. Atherosclerosis is associated with inflammation and the neutrophil/lymphocyte ratio (NLR) is a marker of inflammation whose behavior in postmenopause is unknown. Aim of the study To know the relationship of the NLR with cardiovascular risk markers in premenopausal and postmenopausal women. Material and methods Premenopausal and postmenopausal women were studied, in all of them a complete hemogram and the NLR, platelet/lymphocyte ratio (PLR) were calculated, also glucose and lipids levels were measured. In all of them subcutaneous and visceral fat, carotid intima-media thickness (IMT), epicardial fat were measured by ultrasound Also baseline and and after flow-mediated stimulus the arterial diameter, the pulsatility index and the resistive index of the brachial artery were measured by ultrasound. The results are reported with medians and intervals, Mann-Whitney U and Spearman correlation analysis were performed. Results Eighty two patients were recruited, 41 premenopausal and 41 postmenopausal. When comparing both groups there was no difference in glucose, lipids, NLR, PLR, carotid IMT, epicardial fat, subcutaneous fat, visceral fat or Doppler parameters of the brachial artery. Conclusion NLR was not different between premenopausal and postmenopausal women but abnormal PLR was greater in those postmenopausal with vasomotor symptoms.

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Section: Methodsmentioning

confidence: 99%

Relationship of the neutrophil/lymphocyte ratio with cardiovascular risk markers in premenopausal and postmenopausal women

Carranza-Lira

Montiel

Camacho

et al. 2020

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“…Therefore, echocardiographic evaluation of epicardial fat could serve as a reliable marker of visceral adiposity. Epicardial fat is also associated with clinical and anthropometric parameters of the metabolic syndrome; therefore, echocardiographic evaluation of epicardial fat is considered a simple tool to stratify cardiovascular risk in clinical practice [ 16 ].…”

Section: Introductionmentioning

confidence: 99%

Cardiovascular risk in Cuban adolescents and young adults with congenital adrenal hyperplasia

Espinosa Reyes,

Pesántez Velepucha,

Cabrera Rego

et al. 2023

BMC Endocr Disord

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Background Hyperandrogenism and supraphysiologic glucocorticoid replacement may lead to subclinical atherosclerosis in people with congenital adrenal hyperplasia (CAH) and predispose the development of cardiovascular diseases from an early age. Objectives To determine if cardiometabolic risk factors and subclinical atherosclerosis are more frequent in patients with CAH due to 21-hydroxylase deficiency (21OHD) and if there is an association with clinical, hormonal and treatment of 21OHD. Material and methods A descriptive prospective cross-sectional study exploring clinical variables, biochemical, hormonal variables, endothelial dysfunction (flow-mediated dilation < 5%) and carotid intima media thickness (≥ 95 percentile in adolescents and ≥ 75 percentile in adults) and epicardial fat. Adolescents and young patients with 21OHD were compared with controls matched by age, sex, body mass index and Tanner stage. Results Forty four subjects (22 with CAH), 36 (82%) females, with a mean age of 17.1 ± 5.5 years (range 10–30 years) were included. Family history revealed diabetes, hypertension, and hypercholesterolemia with high frequencies in both groups. The blood pressure was similar in both groups. Blood glucose levels were lower and triglycerides higher in patient (both p < 0.01). Epicardial fat was similar between groups and in patients with CAH it was related to cholesterol levels (r = 0.679, p < 0.01), time since CAH diagnosis (r = 0.462, p = 0.03) and glucocorticoid dose (r = 0.499, p = 0.04). Carotid intima media thickness (CIMT) had a tendency to be increased in patients (p = 0.07) and was directly related to 17-hydroxyprogesterone (r = 0.510, p = 0.018), diastolic blood pressure (r = 0.444, p = 0.04) and the homeostatic model assessment (HOMA) index (r = 0.507, p = 0.01). Endothelial dysfunction was not different between groups. Conclusions Some cardiometabolic risk factors were increased in patients with CAH and were associated with clinical, hormonal and treatment parameters of CAH. Cardiometabolic risk should be evaluated regularly in patients with CAH.

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