Medida do átrio esquerdo em pacientes com suspeita de insuficiência cardíaca com fração de ejeção normal

Jorge, Antônio José Lagoeiro; Ribeiro, Mário Luiz; Rosa, Maria Luiza Garcia; Licio, Fernanda Volponi; Fernandes, Luíz Cláudio; Lanzieri, Pedro Gemal; Jorge, Bruno Afonso Lagoeiro; Brito, Flavia Oliveira Xavier; Mesquita, Evandro Tinoco

doi:10.1590/s0066-782x2012005000009

Cited by 9 publications

(6 citation statements)

References 15 publications

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“…In the present study, changes in heart structure (LV mass, LV mass index, SWT, and left atrial diameter) were present in the LVDD group; these changes did not show any independent correlation with LVDD in multivariate analysis and we estimate that they are consecutive to increased BMI,22,23 rather than as a consequence of LVDD. In addition, we hypothesize that significant structural changes occur at the stage of diastolic heart failure with increased filling pressure rather than with LVDD.…”

Section: Discussioncontrasting

confidence: 53%

“…Conversely, in patients with LVDD, left atrial enlargement may be the consequence of chronic LV pressure elevation, and in this case, indexed left atrial volume (>34 mL/m 2 ) is more reliable than indexed left atrial diameter as a marker of LVDD 22. In the present study, there was no significant difference in left atrial diameter among the three groups, and we hypothesize—as mentioned above—that the indexed volume is a better marker of left atrial remodeling in this setting.…”

Section: Discussionmentioning

confidence: 99%

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Impact of Overweight and Obesity on Left Ventricular Diastolic Function and Value of Tissue Doppler Echocardiography

Kossaify

Nicolas

2013

Clin Med Insights Cardiol

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BackgroundDiastolic dysfunction is a common cause of heart failure with preserved systolic function in obese patients.ObjectiveTo assess diastolic function in a series of overweight and obese patients using conventional and tissue Doppler echocardiography.Setting and methodUniversity hospital; left ventricular diastolic function was evaluated in 99 patients (mean age 61.59 ± 13.9 years); body mass index and waist circumference were assessed, and patients were subdivided into three groups according to their body mass index (kg/m2): [normal, (18.5–24.9); overweight, (25–29.9); obese, (>29.9)]. Peak early (E) and late (A) transmitral flow and peak early (E′) diastolic mitral annulus velocities were measured.ResultsDiastolic dysfunction was significantly higher in the overweight/obese groups compared to the normal body mass index group. The analysis was made with regard to waist circumference and other clinical characteristics, and multivariate regression analysis showed a direct and independent effect of body mass index on diastolic function [OR: 2.75; CI: 1.34–5.67; P = 0.006]. Discussion was made in view of the latest clinical data. Also, an insight into normal weight obesity is presented and discussed.ConclusionOverweight and obesity are found to have an independent negative impact on diastolic function as assessed by tissue Doppler imaging.

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Section: Discussioncontrasting

confidence: 53%

Section: Discussionmentioning

confidence: 99%

Impact of Overweight and Obesity on Left Ventricular Diastolic Function and Value of Tissue Doppler Echocardiography

Kossaify

Nicolas

2013

Clin Med Insights Cardiol

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“…LA size can be used as a marker for chronic elevation of LV filling pressure and is often used to assess diastolic dysfunction in humans ( 83 , 139 ) and animal models ( 17 , 50 , 123 , 171 ). Given the small LA size in mice, strict attention, with respect to probe location, is required for accurate measurements.…”

Section: Echocardiographymentioning

confidence: 99%

Guidelines for measuring cardiac physiology in mice

Lindsey

Kassiri

Virag

et al. 2018

American Journal of Physiology-Heart and Circulatory Physiology

263

194

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Cardiovascular disease is a leading cause of death, and translational research is needed to understand better mechanisms whereby the left ventricle responds to injury. Mouse models of heart disease have provided valuable insights into mechanisms that occur during cardiac aging and in response to a variety of pathologies. The assessment of cardiovascular physiological responses to injury or insult is an important and necessary component of this research. With increasing consideration for rigor and reproducibility, the goal of this guidelines review is to provide best-practice information regarding how to measure accurately cardiac physiology in animal models. In this article, we define guidelines for the measurement of cardiac physiology in mice, as the most commonly used animal model in cardiovascular research.Listen to this article’s corresponding podcast at http://ajpheart.podbean.com/e/guidelines-for-measuring-cardiac-physiology-in-mice/.

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“…Other parameters used in clinical practice to evaluate and characterize DD ventricular remodeling are indexed LV mass and indexed LAV 44 .…”

Section: Echocardiographymentioning

confidence: 99%

Entendendo a disfunção diastólica assintomática na prática clínica

Mesquita¹,

Jorge²

2013

Arq. Bras. Cardiol.

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Medida do átrio esquerdo em pacientes com suspeita de insuficiência cardíaca com fração de ejeção normal

Cited by 9 publications

References 15 publications

Impact of Overweight and Obesity on Left Ventricular Diastolic Function and Value of Tissue Doppler Echocardiography

Impact of Overweight and Obesity on Left Ventricular Diastolic Function and Value of Tissue Doppler Echocardiography

Guidelines for measuring cardiac physiology in mice

Entendendo a disfunção diastólica assintomática na prática clínica

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