Medida do comprimento do osso nasal entre 11 e 15 semanas de gestação em uma população brasileira: estudo preliminar

Abstract

Fetal nasal bone length in the period between 11 and 15 gestational week Cicero et al.(3) have evidenced that the nasal bone was absent in 43 of 59 (73%) fetuses with trisomy 21, and in three of 603 (0.5%) chromosomically normal fetuses between the 11th and 14th gestational weeks. In a recent study, the addition of the nasal bone evaluation to the measurement of nuchal translucency (NT) and maternal biochemical serum screening maintained the rate of detection of trisomy 21 at 90%, however reduced the false positive rates from 5% to 2.5% (4) . It is important to note that the visualization and/or measurement of the nasal bone length between the 11th and 14th gestaCossi PS, Araujo Júnior E, Bussamra LCS, Guimarães Filho HA, Nardozza LMM, Moron AF. Measurement of fetal nasal bone length in the period between 11 and 15 gestational weeks in a Brazilian population: a preliminary study. Radiol Bras. 2008;41(3):155-158.

A Thai Reference for Normal Fetal Nasal Bone Length at 11–13(+6) Weeks Gestation

“…Our study showed that the incidence of hypoplasia or absent nasal bone is low among normal fetuses of Thai women. This is consistent with previous reports [9,10,11,15]. Another possible cause for the difference in the incidence of absent nasal bones was a technical factor or error.…”

“…NBLs in our Thai population are similar to those reported for Korean and Latin-American populations, but differ from those reported for Caucasian, African-American and Chinese populations [10,13,15,16,17,18] as shown in table 1. Our study’s results correlate with studies of NBL in Thai population in the second trimester that showed significant differences in the median and 5th percentile NBL between white, African-American, and Thai populations [19,20].…”

“…Women of African-Caribbean have a higher incidence of hypoplastic or absent nasal bone in comparison to Caucasian women, but the incidence is not different when compared to that of Asian women [9,10]. Our study showed that the incidence of hypoplasia or absent nasal bone is low among normal fetuses of Thai women.…”

“…The effects of ethnicity on NBL has been reported. In particular, women of African-Caribbean origin have a higher incidence of hypoplastic nasal bones in comparison to Caucasian women, but the incidence does not differ from that of Asian women [9,10]. However, large studies of Chinese women have shown contradictory effects of ethnicity on the measurement of NBL [11,12].…”

Anatomics comparative aspects of head bones of domestic animals and adult human

“…Such findings coincided with those of Getty (1986) and Lana et al (2012). In contrast, in humans, the nasal bone is small and rectangular (PUTZ; PABST, 1995;COSSI et al, 2008).…”