Mediterranean Diet and Bladder Cancer Risk in Italy

Bravi, Francesca; Spei, Maria-Eleni; Polesel, Jerry; Maso, Matteo Di; Montella, Maurizio; Ferraroni, Monica; Serraino, Diego; Libra, Massimo; Negri, Eva; Vecchia, Carlo La; Turati, Federica

doi:10.3390/nu10081061

Cited by 35 publications

(34 citation statements)

References 45 publications

(55 reference statements)

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“…However, this study did not sufficiently adjust for smoking behavior. Finally, an Italian hospital-based case-control study found higher MD adherence to be associated with a significantly decreased UCC risk (47).…”

Section: Schulpen and Van Den Brandtmentioning

confidence: 93%

Adherence to the Mediterranean Diet and Risks of Prostate and Bladder Cancer in the Netherlands Cohort Study

Schulpen

Brandt

2019

Cancer Epidemiology, Biomarkers &Amp; Prevention

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Background: Prostate cancer and urinary bladder cancer are frequently occurring cancers with few risk factors identified. We examined the relation of Mediterranean diet (MD) adherence with risks of prostate and bladder cancer in the Netherlands Cohort Study (NLCS). Methods: Data were available for 58,279 men and 62,573 women, who completed a baseline questionnaire on diet and other cancer risk factors. Multiple MD scores, including the alternate Mediterranean diet score without alcohol (aMEDr), were calculated to assess MD adherence. After 20.3 years of follow-up, 3,868 prostate cancer cases (advanced: 1,256) and 1,884 bladder cancer cases could be included in multivariable Cox proportional hazards analyses. Results: aMEDr was not associated with advanced prostate cancer risk [hazard ratio (HR) per 2-point increment (95% confidence interval, 95% CI) ¼ 1.06 (0.96-1.17)]. In contrast, higher aMEDr values were associated with a significantly increased risk of nonadvanced prostate cancer (P trend ¼ 0.04). For bladder cancer risk, no association was observed with aMEDr [HR per 2-point increment (95% CI) ¼ 1.00 (0.92-1.09)]. Absolute scores based on the World Cancer Research Fund/American Institute for Cancer Research (WCRF/AICR) dietary recommendations were not associated with prostate or bladder cancer risk. Conclusions: MD adherence, measured by aMEDr or other MD scores, was not associated with decreased risks of advanced prostate cancer and bladder cancer in the NLCS. Higher levels of care-seeking behavior, screening attendance, and prostate cancer awareness in higher educated men with healthier lifestyles could potentially explain the positive associations observed for nonadvanced prostate cancer risk. Impact: MD adherence does not seem to reduce the risk of (advanced) prostate cancer or bladder cancer.

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Section: Schulpen and Van Den Brandtmentioning

confidence: 93%

Adherence to the Mediterranean Diet and Risks of Prostate and Bladder Cancer in the Netherlands Cohort Study

Schulpen

Brandt

2019

Cancer Epidemiology, Biomarkers &Amp; Prevention

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“…More recently, research has considered this in regard to other health outcomes, such as the quality and quantity of sleep [ 3 , 4 ], cognitive decline, and cognitive functions [ 5 ]. The most studied dietary pattern has been the Mediterranean diet, which has shown beneficial effects, such as a lower incidence of major cardiovascular events among persons at high risk for cardiovascular conditions [ 6 ] and a lower risk for certain types of cancer [ 7 , 8 ]. Changes in macronutrient intake indicate a progressive trend towards a decrease in carbohydrate intake at the expense of an increase in the consumption of total fat and other unhealthy fat subtypes as well as an increased protein intake [ 9 , 10 , 11 ].…”

Section: Introductionmentioning

confidence: 99%

The Effectiveness of a Smartphone Application on Modifying the Intakes of Macro and Micronutrients in Primary Care: A Randomized Controlled Trial. The EVIDENT II Study

Recio-Rodríguez¹,

Conde²,

Calvo-Aponte

et al. 2018

Nutrients

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Background: This study evaluates the effectiveness of adding a diet smartphone application to standard counseling to modify dietary composition over the long term (12 months). Methods: A randomized, controlled, multicenter clinical trial was conducted involving the participation of 833 subjects from primary care clinics (415 to the intervention (counseling + application) group (IG) and 418 to the control (counseling) group (CG)). Both groups were counseled about a healthy diet and physical activity. For the 3-month intervention period, the IG was also trained to use a diet smartphone application that involved dietary self-monitoring and tailored feedback. Nutritional composition was estimated using a self-reported food frequency questionnaire. Results: An analysis of repeated measures revealed an interaction between the group and the percentages of carbohydrates (p = 0.031), fats (p = 0.015) and saturated fats (p = 0.035) consumed. Both groups decreased their energy intake (Kcal) at 12 months (IG: −114 (95% CI: −191 to −36); CG: −108 (95% CI: −184 to −31)). The IG reported a higher percentage intake of carbohydrates (1.1%; 95% CI: 0.1 to 2.0), and lower percentage intakes of fats (−1.0%; 95% CI: −1.9 to −0.1) and saturated fats (−0.4%; 95%CI: −0.8 to −0.1) when compared to the CG. Conclusions: Better results were achieved in terms of modifying usual diet composition from counseling and the diet smartphone application compared to counseling alone. This was evaluated by a self-reported questionnaire, which indicated an increased percentage intake of carbohydrates, and decreased percentage intakes of fats and saturated fats.

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“…High consumption of alcohol, 22,23 low consumption of vegetables and fruits, and low levels of drinking water, 24 also, consumption of water containing halo methane chloride, 16,25 Schistosoma infection (9-25%), and occupational exposure to aromatic amines, 26 Chronic bladder infection, history of diabetes, and metabolic syndrome 27 are associated with the risk of developing BC. In this study, the association between alcohol consumption and malnutrition was reported to be around 9-57% (Table 1), the majority of studies in the world also refer to the relationship between alcohol and BC.…”

Section: Lifestylementioning

confidence: 99%

<p>Bladder Cancer in Iran: An Epidemiological Review</p>

Farmanfarma¹,

Mahdavifar²,

Salehiniya³

2020

RRU

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Bladder cancer is the sixth most common cancer in Iran. Information about the epidemiological situation of the disease and its risk factors is necessary for conducting a planning program to reduce the disease. This study is conducted with the aim of evaluating the epidemiological features of bladder cancer in Iran. Methods: This is a systematic review of the published articles in both Persian and English in international and national journals during the years 2000-2019 with key words of Iran and bladder cancer. Articles were selected from the national information database (SID, Magiran) and international databases (PubMed, Scopus, and Web of Science). Articles related to the epidemiological aspects of the disease, including incidence, prevalence, mortality, and risk factors, were evaluated. Results: The incidence rate of bladder cancer was about 1.6-115; cumulative survival rate was 0.95, mortality rate was 0.5-0.84 and its prevalence in the Iranian population was between 4.10% and 12.8%. The risk of developing malignancy in major risk factor groups, including smoking and opium, was 6.2 (2.04-18.7), increases in protein and animal fat consumption were about 5-and 19-times higher than in the general population, respectively. In terms of occupational exposure, bus and heavy truck drivers were 11.3 (1.3-92.05) more at risk than others. Conclusion: Regarding the increasing trend of this disease, changes in lifestyle to reduce risk factors can be effective in decreasing the incidence and mortality rate of this malignancy.

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Mediterranean Diet and Bladder Cancer Risk in Italy

Cited by 35 publications

References 45 publications

Adherence to the Mediterranean Diet and Risks of Prostate and Bladder Cancer in the Netherlands Cohort Study

Adherence to the Mediterranean Diet and Risks of Prostate and Bladder Cancer in the Netherlands Cohort Study

The Effectiveness of a Smartphone Application on Modifying the Intakes of Macro and Micronutrients in Primary Care: A Randomized Controlled Trial. The EVIDENT II Study

<p>Bladder Cancer in Iran: An Epidemiological Review</p>

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