Medium- and long-term survival after pacemaker implant: Improved survival with right ventricular outflow tract pacing

Vanerio, Gabriel; Vidal, Juan L.; Banizi, Pablo Fernández; Aguerre, Daniel Banina; Viana, Pablo; Tejada, Jorge

doi:10.1007/s10840-008-9238-x

Cited by 28 publications

(15 citation statements)

References 28 publications

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“…Unfortunately, the majority of the studies involved short-term follow-up studies. A recent retrospective study demonstrated a better survival in patients with RV outflow tract pacing as compared with RV apical pacing (81). The favorable effect of RV outflow tract pacing may be related to the more physiologic activation pattern, resulting in less LV dyssynchrony.…”

Section: Alternative Rv Pacing Sitesmentioning

confidence: 99%

The Effects of Right Ventricular Apical Pacing on Ventricular Function and Dyssynchrony

Tops

Schalij

Bax

2009

Journal of the American College of Cardiology

360

235

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Cardiac pacing is the only effective treatment for patients with sick sinus syndrome and atrioventricular conduction disorders. In cardiac pacing, the endocardial pacing lead is typically positioned at the right ventricular (RV) apex. At the same time, there is increasing indirect evidence, derived from large pacing mode selection trials and observational studies, that conventional RV apical pacing may have detrimental effects on cardiac structure and left ventricular function, which are associated with the development of heart failure. These detrimental effects may be related to the abnormal electrical and mechanical activation pattern of the ventricles (or ventricular dyssynchrony) caused by RV apical pacing. Still, it remains uncertain if the deterioration of left ventricular function as noted in a proportion of patients receiving RV apical pacing is directly related to acutely induced left ventricular dyssynchrony. The upgrade from RV pacing to cardiac resynchronization therapy may partially reverse the deleterious effects of RV pacing. It has even been suggested that selected patients with a conventional pacemaker indication should receive cardiac resynchronization therapy to avoid the deleterious effects. This review will provide a contemporary overview of the available evidence on the detrimental effects of RV apical pacing. Furthermore, the available alternatives for patients with a standard pacemaker indication will be discussed. In particular, the role of cardiac resynchronization therapy and alternative RV pacing sites in these patients will be reviewed.

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Section: Alternative Rv Pacing Sitesmentioning

confidence: 99%

The Effects of Right Ventricular Apical Pacing on Ventricular Function and Dyssynchrony

Tops

Schalij

Bax

2009

Journal of the American College of Cardiology

360

235

View full text Add to dashboard Cite

show abstract

“…When RV pacing is inevitable, the His bundle [42,43], right ventricular outflow tract [44,45] and right ventricular septum [46,47] have been studied as alternate pacing sites. Selectively pacing these sites may reduce pacing induced ventricular dyssynchrony [48-50] and potentially result in a reduction in ventricular volumes with improved LV function compared to RV apical pacing.…”

Section: Minimizing the Detrimental Effects Of Rv Pacingmentioning

confidence: 99%

The Downside of Right Ventricular Apical Pacing

Brenyo

Goldenberg

Barsheshet

2012

Indian Pacing and Electrophysiology Journal

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The right ventricular (RV) apex has been the standard pacing site since the development of implantable pacemaker technology. Although RV pacing was initially only utilized for the treatment of severe bradyarrhythmias usually due to complete heart block, today the indications for and implantation of RV pacing devices is dramatically larger. Recently, the adverse effects of chronic RV apical pacing have been described including an increased risk of heart failure and death. This review details the detrimental effects of RV apical pacing and their shared hemodynamic pathophysiology. In particular, the role of RV apical pacing induced ventricular dyssynchrony is highlighted with a specific focus on differential outcome based upon QRS morphology at implant.

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“…Исследования со стимуляцией из альтернативных то-чек (межжелудочковая перегородка, выходной тракт пра-вого желудочка) продемонстрировали спорные результа-ты [11,16,38,47]. В то же время бивентрикулярная стиму-ляция может иметь преимущества не только у пациентов с выраженной систолической дисфункцией, но и при со-хранной или умеренно сниженной ФВ ЛЖ [6,19,44].…”

Section: заключениеunclassified

Importance of the heart failure mechanisms during permanent single-chamber cardiac pacing for optimization of rate-adaptive mode

Kuznetsova¹,

Андреев²,

Сыркин³

et al. 2015

Kardiol. serdechno-sosud. khir.

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При постоянной электрокардиостимуляции сердца риск сердечной недостаточности (СН) повышен. В настоящем обзоре освещены механизмы развития СН при однокамерной электрокардиостимуляции сердца и основные подходы к преодолению данной проблемы. Особое внимание уделено обсуждению возможностей оптимизации режима частотной адаптации для уменьшения СН. Ключевые слова: постоянная однокамерная электрокардиостимуляция сердца, апикальная правожелудочковая стимуля-ция, хронотропная некомпетентность, сердечная недостаточность, режим частотной адаптации.The risk of heart failure in increased in case of permanent cardiac pacing. Heart failure mechanisms during permanent singlechamber cardiac pacing and main approaches to overcome these problems are being discussed in the review. Possibilities to optimize rate-adaptive modes for heart failure reducing are emphasized.Keywords: permanent single-chamber cardiac pacing, apical right ventricular pacing, chronotropic incompetence, heart failure, rate-adaptive mode.

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Medium- and long-term survival after pacemaker implant: Improved survival with right ventricular outflow tract pacing

Abstract: Outflow tract pacing appears to improve medium- and long-term survival. Prospective randomized trials with a greater amount of patients are necessary to confirm the findings of this study.

Cited by 28 publications

References 28 publications

The Effects of Right Ventricular Apical Pacing on Ventricular Function and Dyssynchrony

The Effects of Right Ventricular Apical Pacing on Ventricular Function and Dyssynchrony

The Downside of Right Ventricular Apical Pacing

Importance of the heart failure mechanisms during permanent single-chamber cardiac pacing for optimization of rate-adaptive mode

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