Medium-term Outcomes after Whole-gland High-intensity Focused Ultrasound for the Treatment of Nonmetastatic Prostate Cancer from a Multicentre Registry Cohort

Dickinson, Louise; Arya, Manit; Afzal, Naveed; Cathcart, Paul; Charman, Susan C.; Cornaby, Andrew; Hindley, Richard G.; Lewi, Henry; McCartan, Neil; Moore, Caroline M.; Nathan, Senthil; Ogden, Chris; Persad, Rajendra; Meulen, Jan van der; Weir, Shraddha; Emberton, Mark

doi:10.1016/j.eururo.2016.02.054

Cited by 57 publications

(39 citation statements)

References 32 publications

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“…0.58 mm in longitudinal diameter, 1 mm in transverse diameter and 6.4 mm in acoustic axis), is created for each pulse of energy. The risk of fistulae in prostate cancer treated with HIFU is estimated to be 0.13% and is lower than the risk of 1.6–2.8% reported in the surgical management of rectal DIE.…”

Section: Disclosurementioning

confidence: 75%

Transrectal high‐intensity focused ultrasound as focal therapy for posterior deep infiltrating endometriosis

Dubernard

Gelet

Lafon

et al. 2018

Ultrasound in Obstet & Gyne

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Section: Disclosurementioning

confidence: 75%

Transrectal high‐intensity focused ultrasound as focal therapy for posterior deep infiltrating endometriosis

Dubernard

Gelet

Lafon

et al. 2018

Ultrasound in Obstet & Gyne

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“…Four studies (4.8%) related to preclinical research (IDEAL phase 0). The 43 remaining original research studies that applied IDEAL were mapped to the corresponding IDEAL stage: IDEAL with nine (20.9%), 27 (62.8%), four (9.3%), 0 (0%), and three (7.0%) publications, respectively .…”

Section: Resultsmentioning

confidence: 99%

“…These studies were published in European Urology and BJUI . All three Long‐term studies followed the IDEAL framework and were published in European Urology , BMJ and World Journal of Urology .…”

Section: Resultsmentioning

confidence: 99%

Use of the IDEAL framework in the urological literature: where are we in 2018?

2019

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ObjectivesTo assess uptake and application of the IDEAL principles in original surgical procedure-or device-related clinical research studies, as well as its reported relevance as characterized by secondary publications, editorials and reviews. ConclusionsThe IDEAL framework has found widespread adoption in the urology literature as witnessed by a large number of original manuscripts and secondary publications citing IDEAL; however, its application is largely limited to the early stages of surgical innovation, frequently with inappropriate and incomplete implementation. Further efforts are needed to guide investigators in the optimal use of the IDEAL framework as it relates to surgical innovation in urology.Abbreviation: IQR, interquartile range.

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“…Long‐term data are still not available for evaluation of HIFU therapy . However, in the largest study to date with 569 patients and 5‐year follow‐up, Dickinson et al indicated that HIFU was a reasonable choice for the treatment of nonmetastatic prostate cancer. Heterogeneity in patient selection and insufficient evidence are the major limitations at this time for concluding that focal treatment therapy with HIFU is as effective as more‐traditional invasive therapy, although as more studies emerge, it is clear that focal HIFU therapy in the appropriate circumstances is very promising …”

Section: High‐intensity Focused Us As a Primary Treatment Optionmentioning

confidence: 99%

“…Research into the use of HIFU has been ongoing since the 1990s, and at this time, more than 65,000 patients with prostate cancer have been treated with HIFU in Europe . Compared to the other modalities, HIFU ablation offers advantages over other therapies, especially the lack of substantial injury to tissues outside the treatment zone . A major advantage is that HIFU is completely noninvasive and does not require the insertion of probes into the target tissue .…”

mentioning

confidence: 99%

Histotripsy: The Next Generation of High‐Intensity Focused Ultrasound for Focal Prostate Cancer Therapy

Dubinsky

Khokhlova

et al. 2019

J of Ultrasound Medicine

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This article reviews the most current methods and technological aspects of highintensity focused ultrasound (HIFU), which is termed histotripsy. The rationale for focal therapy for prostate carcinoma rather than prostatectomy, which is being used extensively throughout Europe and Asia, is presented, and an argument for why HIFU is the modality of choice for primary therapy and recurrent disease is offered. The article presents a review of the technical advances including higher ultrasound beam energy than current thermal HIFU which allows for more accurate tissue targeting, less collateral tissue damage, and faster treatment times. Finally, the article presents a discussion about the advantage of ultrasound guidance for histotripsy in preference to magnetic resonance imaging guidance primarily based on cost, ease of application, and portability.

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Medium-term Outcomes after Whole-gland High-intensity Focused Ultrasound for the Treatment of Nonmetastatic Prostate Cancer from a Multicentre Registry Cohort

Cited by 57 publications

References 32 publications

Transrectal high‐intensity focused ultrasound as focal therapy for posterior deep infiltrating endometriosis

Transrectal high‐intensity focused ultrasound as focal therapy for posterior deep infiltrating endometriosis

Use of the IDEAL framework in the urological literature: where are we in 2018?

Histotripsy: The Next Generation of High‐Intensity Focused Ultrasound for Focal Prostate Cancer Therapy

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