1996
DOI: 10.1097/00003072-199603000-00006
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Medullary Thyroid Carcinoma Imaged by Tc-99m MIBI SPECT and Tl-201 Chloride/Tc-99m Pertechnetate Subtraction SPECT

Abstract: A 61-year-old man with medullary thyroid carcinoma and local invasion of the left lobe of the thyroid had Tc-99m MIBI SPECT and Tl-201 chloride/Tc-99m pertechnetate subtraction SPECT after left lobectomy of the thyroid, using a triple-headed gamma camera. Tl-201 chloride/Tc-99m pertechnetate subtraction demonstrated a large mass with high Tl-201 uptake in the left neck. Although there was intense uptake in the tumor in the left thyroid bed on Tc-99m MIBI neck SPECT, there was also uptake in both salivary gland… Show more

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Cited by 4 publications
(2 citation statements)
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“…Different photon energies emitted by different radioisotopes can then be used to assign ''colors'' to a nuclear image. Clinical applications include SPECT for thyroid and parathyroid imaging in which radioactive iodine and thallium are used together 173,174 as well as in cardiac scintigraphy where radioactive technetium and thallium may be combined. [169][170][171] For instance, in the assessment of acute myocardial ischemia 201 Tl is used to identify areas with patent blood flow and 99m Tc-labelled myosin antibody-fragment is used to identify areas of damaged myocardium by detection of exposed myosin fibers.…”
Section: B2 Multi-color Imaging Probesmentioning
confidence: 99%
“…Different photon energies emitted by different radioisotopes can then be used to assign ''colors'' to a nuclear image. Clinical applications include SPECT for thyroid and parathyroid imaging in which radioactive iodine and thallium are used together 173,174 as well as in cardiac scintigraphy where radioactive technetium and thallium may be combined. [169][170][171] For instance, in the assessment of acute myocardial ischemia 201 Tl is used to identify areas with patent blood flow and 99m Tc-labelled myosin antibody-fragment is used to identify areas of damaged myocardium by detection of exposed myosin fibers.…”
Section: B2 Multi-color Imaging Probesmentioning
confidence: 99%
“…One approach to increase the information is to use multiplex imaging with an additional imaging agent. Multi contrast agent applications include SPECT in the thyroidandparathyroid 1719 and cardiac scintigraphy, 2023,4851 both of which can simultaneously detect two different imaging agents (ie, 99m Tc, 123 I, 111 In, and 201 Tl) with the energy resolution features of gamma cameras (figure 1B). These methods rely on the use of two different agents, each targeting a different process, and simultaneously acquiring data from each.…”
Section: Multiple Colour Reagentsmentioning
confidence: 99%