Medulloblastoma during pregnancy: Hormone-mediated association? Report of 2 cases

Headache is a common complaint during pregnancy and the puerperium. The differentiation between a benign headache and a headache that has an underlying more endangering cause, such as an intracranial tumor, can be difficult and often requires diagnostic procedures and brain imaging techniques. We report the case of an 18-year-old female patient who developed clinical symptoms—persistent headache followed by neurological deficit—in the last part of her pregnancy. A medulloblastoma (MB) was diagnosed and treated after delivery. We review 11 other cases of MB in pregnancy reported in the literature. The most common clinical manifestation at diagnosis was headache followed by neurological deficits. We discuss the association of brain tumor growth with physiological changes during pregnancy. We conclude that clinical features of intracranial tumors can be misinterpreted as pregnancy-related symptoms and should not be dismissed.

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Medulloblastoma during pregnancy: Hormone-mediated association? Report of 2 cases

Cited by 2 publications

References 25 publications

Diagnosis of medulloblastoma in pregnant women: To continue with the pregnancy or not? A case report and literature review

Diagnosis of medulloblastoma in pregnant women: To continue with the pregnancy or not? A case report and literature review

Medulloblastoma Presenting as Severe Headache during Pregnancy: A Case Report and Review of the Literature

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