Medulloblastoma in the cerebellopontine angle mimicking a schwannoma

Dung, Le Thanh; Duc, Nguyen Minh

doi:10.1002/ccr3.3912

Cited by 2 publications

(4 citation statements)

References 16 publications

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“…Following the application of chosen criteria, we found only 21 cases of medulloblastoma associated with auditory dysfunction 5,7,11,[14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29] (Table 1). In this study, a gender predominance for male was found (52.3% males, 47.6% females); 38% of the patients were children and 62% of the patients were adults, with a mean age of 23 years (between 2 and 50 years).…”

Section: Resultsmentioning

confidence: 99%

“…It was reported that in some patients with hearing loss, tinnitus or dizziness, unexpectedly, the computer tomography scan of petrous bones did not show any lesion at the level of the internal auditory canal, but on the MRI examination, a lesion was noted in the cerebellopontine angle as a homogenous solid mass which appeared hyperintense on T2-weighted image 5,33 .…”

Section: Radiologic Criteria For Medulloblastomasmentioning

confidence: 97%

“…On CT imaging, it may appear as a heterogeneous mass in the cerebellopontine angle 7,47 . One must keep in mind that the acoustic schwannoma is the most frequent tumor found in the cerebellopontine angle, and the most important tumor with which the differential diagnosis of medulloblastoma should be made 5 .…”

Section: Differential Diagnosis Of Cerebellopontine Angle Medulloblas...mentioning

confidence: 99%

“…There are some controversies about the origin of cerebellopontine angle (CPA) medulloblastoma. A theory described that CPA medulloblastoma is formed from a remnant of the lateral medullary velum which proliferates into the cerebellopontine angle 5,6 . The origin of extra-axial medulloblastoma in the cerebellopontine angle may appear because of the extension from the midline of the cerebellum through the foramina of Luschka or arising directly from the surface of the external germinal layer of the pons or cerebellum; or it may appear in the tentorial region 7 .…”

Section: Introductionmentioning

confidence: 99%

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Unusual manifestation of cerebellopontine angle medulloblastoma with tinnitus and sensorineural hearing loss

Bejenariu

Milea

Sarafoleanu

2023

Romanian Journal of Rhinology

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BACKGROUND. Medulloblastoma is the most common central nervous system embryonal tumor in children. In adults, this tumor is extremely rare, accounting for nearly 1% of primary brain tumors. Raised intracranial pressure signs are common manifestations of posterior fossa tumors, but tinnitus and/or sensorineural hearing loss are very uncommon presenting symptoms. MATERIAL AND METHODS. Starting from a very rare case of a 39-year-old male with left tinnitus and progressive left sensorineural hearing loss as isolated symptoms of a medulloblastoma, we performed a literature survey using the PubMed, ProQuest, Web of Science, Science Direct, Wiley Online search engines for patients with medulloblastoma and tinnitus and/or sensorineural hearing loss. RESULTS. All patients found in the relevant literature with auditory dysfunctions presented sensorineural hearing loss. Other frequent manifestations were: ataxia, facial numbness, vertigo, headache, nystagmus. Two patients were found with tinnitus and sensorineural hearing loss as isolated symptoms of medulloblastoma, as in our case, and in two other cases the sensorineural hearing loss was the unique symptom. With refers to the onset of medulloblastoma, just 3 patients had the first symptoms sensorineural hearing loss and tinnitus. Concerning the tumor location, in patients manifested with isolated tinnitus and sensorineural hearing loss, like our patient, the tumor arised from the internal auditory meatus, extended to the cerebellopontine angle or involved the vestibulocochlear nerve. With regards to treatment, surgery in association with radiotherapy and chemotherapy was elected in most cases (38%). CONCLUSION. It is important to pay attention at patients with isolated auditory dysfunction that may mimic significant posterior fossa tumors, such as a medulloblastoma.

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Section: Resultsmentioning

confidence: 99%

Section: Radiologic Criteria For Medulloblastomasmentioning

confidence: 97%

Section: Differential Diagnosis Of Cerebellopontine Angle Medulloblas...mentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Unusual manifestation of cerebellopontine angle medulloblastoma with tinnitus and sensorineural hearing loss

Bejenariu

Milea

Sarafoleanu

2023

Romanian Journal of Rhinology

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Low apparent diffusion coefficient in an extracranial brain tumor: a case report

et al. 2022

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Background Medulloblastoma is well known as the most common malignant brain tumor identified in children, frequently found at an intra-axial location in the posterior cranial fossa. Extra-axial medulloblastoma is uncommon and often misdiagnosed. We believe that a thorough understanding of atypical medulloblastoma cases is important in daily practice. Case presentation We present the unique case of a 39-year-old woman of Asian descent who suffered from headaches and right-sided hearing impairment. A right extra-axial medulloblastoma with an extremely low apparent diffusion coefficient of 0.404 × 10−3 mm2/second was detected on magnetic resonance imaging. The initial diagnosis suggested schwannoma or hemangioblastoma. However, the postoperative histopathologic findings indicated medulloblastoma (World Health Organization grade IV). Pre- and postoperative magnetic resonance imaging revealed no drop metastasis, but adjuvant radiation therapy was still required as a standard treatment therapy Conclusions Extra-axial medulloblastoma is an uncommon tumor that is often mistaken for other cerebellopontine angle neoplasms. We describe a rare example of extra-axial medulloblastoma, characterized by a low apparent diffusion coefficient. When evaluating an atypical cerebellopontine angle neoplasm, the apparent diffusion coefficient should be considered a relevant indicator.

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Medulloblastoma in the cerebellopontine angle mimicking a schwannoma

Abstract: The typical distinction between cerebellopontine angle (CPA) medulloblastoma and other primary CPA tumors was not fully known. While CPA medulloblastoma is very uncommon, it should be included in the differential diagnosis of patients with CPA tumors.

Cited by 2 publications

References 16 publications

Unusual manifestation of cerebellopontine angle medulloblastoma with tinnitus and sensorineural hearing loss

Unusual manifestation of cerebellopontine angle medulloblastoma with tinnitus and sensorineural hearing loss

Low apparent diffusion coefficient in an extracranial brain tumor: a case report

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