"Medulloepithelioma, An Embryonal Tumor of the Central Nervous System, the Eye and the Optic Nerve: Review of the Clinical Behavior, Cytogenetic and Molecular Characteristics"

Abstract

embryonic development [3]. These cells are multipotent with divergent differentiation capability towards the neuronal, astrocytic, and ependymal lines. Tumoral cells of the CNS -PNET group share these same characteristics.

Intraocular neuroectodermal embryonal tumor in two rabbits

“…Primary embryonal tumors occur in the central and peripheral nervous system, and in the eye. These tumors derive from neuroectodermal cells of the neurotube, the primitive progenitor cells of the nervous system 11 . In the eye, these cells give rise to the optic vesicle and later, the optic cup.…”

“…In the eye, these cells give rise to the optic vesicle and later, the optic cup. Neoplastic transformation results in medulloepithelioma or retinoblastoma (if there is retinal differentiation) 11 …”

“…These tumors derive from neuroectodermal cells of the neurotube, the primitive progenitor cells of the nervous system. 11 In the eye, these cells give rise to the optic vesicle and later, the optic cup. Neoplastic transformation results in medulloepithelioma or retinoblastoma (if there is retinal differentiation).…”

“…Neoplastic transformation results in medulloepithelioma or retinoblastoma (if there is retinal differentiation). 11 Intraocular embryonal tumors are comprised of primitive neuroblasts that form tubules or rosettes with or without luminal ciliary processes. 12 The rosettes are either Flexner-Wintersteiner rosettes with empty lumen, or Homer Wright rosettes with central luminal processes.…”