Meeting the Challenge of Building Diamondoid Medical Nanorobots

Abstract

The technologies that are needed for the atomically precise fabrication of diamondoid nanorobots in macroscale quantities at low cost require the development of a new nanoscale manufacturing technology called positional diamondoid molecular manufacturing, enabling diamondoid nanofactories that can build nanorobots. Achieving this new technology will require the significant further development of four closely related technical capabilities: (1) diamond mechanosynthesis1 (2) programmable positional assembly1 (3) massively parallel positional assembly1 and (4) nanomechanical design. The Nanofactory Collaboration is coordinating a combined experimental and theoretical effort involving direct collaboration among dozens of researchers at multiple institutions in four countries to explore the feasibility of positionally controlled mechanosynthesis of diamondoid structures using simple molecular feedstocks, which is the first step along a direct pathway to developing working nanofactories that can fabricate diamondoid medical nanorobots.

Building nanoparticles using diamondoids structures as a carrier of the drug: Density functional theory study

“…The respirocyte would be a bloodborne spherical 1-micron diamondoid 1000. This nanorobot would deliver 236 times more oxygen to body tissues per unit volume than natural red cells [5].In this study can be used diamandoids as a carrier for the drug. It can be bonded the apraclonidine with chemical formula (C 9 H 10 Cl 2 N 4 ) drug with dimantane, where apraclonidine Solution contains apraclonidine hydrochloride, an alpha adrenergic agonist, in a sterile isotonic solution for topical application to the eye.…”

“…In this study used dimantane with chemical formula (C 14 H 20 ) (Figure 1) show the geometrically optimized of AlP dimantane,Apraclonidine and AlP dimantane bonded with Apraclonidine [4]. The ability to build complex diamondoid medical nanorobots (Freitas 1998(Freitas , 2000a(Freitas , 2005a(Freitas , 2006(Freitas , 2007 to molecular precision, and then to build them cheaply enough in sufficiently large numbers to be useful therapeutically will revolutionize the practice of medicine (Freitas 2008) and surgery (Freitas 2005b). The first theoretical design study of a complete medical nanorobot ever published in a peer-reviewed journal described a hypothetical artificial mechanical red blood cell or "respirocyte" made of 18 billion precisely arranged structural atoms (Freitas 1998).…”

Chemical robotics — chemotactic drug carriers

“…One can describe this idea as a "top-down" approach using miniaturization of devices existing at higher scales. As a possible application he also proposed that a small machine (nanorobot) could be built using his "top-down" approach and put inside the blood vessel in the living body so that it might go to a specific location to carry out surgery with its special knife and tools or to deliver drugs to cure diseases [3].…”