MEG8 as an antagonistic pleiotropic mechanism in breast cancer
Eva M. Verdugo-Sivianes,
Asunción Espinosa-Sánchez,
Ildefonso Cases
et al.
Abstract:Cellular senescence connects aging and cancer. Cellular senescence is a common program activated by cells in response to various types of stress. During this process, cells lose their proliferative capacity and undergo distinct morphological and metabolic changes. Senescence itself constitutes a tumor suppression mechanism and plays a significant role in organismal aging by promoting chronic inflammation. Additionally, age is one of the major risk factors for developing breast cancer. Therefore, while senescen… Show more
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