Small Animal Soft Tissue Surgery 2012
DOI: 10.1002/9781118997505.ch41
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Megacolon

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“…The pathophysiology of megacolon is described as a colonic distension and chronic obstipation that eventually renders the colonic muscle non-functional, leading to irreversible changes in colonic smooth muscle and nerves, and causing inertia. 12 Outlet obstruction will initially result in the development of a hypertrophic megacolon, often reversible with the early removal of the colonic outflow obstruction. 13 The degree of distension and the time needed to produce irreversible changes are unknown, although both are likely to be important factors.…”
Section: Discussionmentioning
confidence: 99%
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“…The pathophysiology of megacolon is described as a colonic distension and chronic obstipation that eventually renders the colonic muscle non-functional, leading to irreversible changes in colonic smooth muscle and nerves, and causing inertia. 12 Outlet obstruction will initially result in the development of a hypertrophic megacolon, often reversible with the early removal of the colonic outflow obstruction. 13 The degree of distension and the time needed to produce irreversible changes are unknown, although both are likely to be important factors.…”
Section: Discussionmentioning
confidence: 99%
“…Some authors have suggested that pelvic osteotomies are only advised if the megacolon has been present for less than 6 months; otherwise, the changes on the colonic wall are deemed to be permanent and subtotal colectomy is the recommended procedure. 3 , 12 However, distraction osteotomy procedures have been reported in two cats with obstipation and constipation of 6 months’ and 8 months’ duration, respectively, both with excellent outcomes. 14 …”
Section: Discussionmentioning
confidence: 99%