Melanoma in situ of penis

Abstract

Considering that at the sixth clinical follow-up the patient was alive and disease free at 50 months after surgery, the chosen treatment has proved successful.

Cutaneous and Mucosal Melanomas of Uncommon Sites: Where Do We Stand Now?

“…The topical use of imiquimod has been reported in the literature in cases of in-situ lesions or inoperable diseases, with variable clinical responses [ 77 , 96 , 97 ]. Further studies are warranted to understand the factors improving the outcomes of these patients.…”

Penile melanoma

“…Primary penile melanoma (MPP) is a rare neoplasm that affects less than 1.4% of primary penile carcinomas and affects mainly patients in the sixth and seventh decade of life. [1,2] According to the histological origin of the tumor, penile melanomas can be divided into cutaneous and mucous. The cutaneous subtype is located on the penile shaft and corresponds to 9% of the locations.…”

“…The mucous subtype is located in the glans (55%), foreskin (28%) and urethral meatus (8%). [1,4] One of the greatest challenges of MPP is its early diagnosis, since its initial presentation may be indistinguishable from benign injury. MPP can present as a black, brown, bluish, reddish or even amelanotic pigmented lesion.…”

“…Primary penile melanoma is an aggressive and rare neoplasm (less than 1.4% of primary penile cancers) that affects patients in the sixth and seventh decade of life. [1,2] The first case was described by Muchison, in 1859. [3] Histologically, it is classified as cutaneous or mucous (most frequent).…”

“…The mucous melanoma is located mainly in the glans (55%), foreskin (28%), and urethral meatus (8%). [1,4] The curative treatment is related to the excision of the tumor in its initial growth phase, so the requirement for an early diagnosis of these lesions is well established.…”