Melanoma of the lower female genital tract (vulva, vagina, and cervix): literature review and own cases

The article deals with the problems of surgical treatment of skin melanoma. Modern surgical treatment of skin melanoma includes various surgical interventions: wide excision of primary skin melanoma, amputation of the finger or disarticulation of the phalanx of the finger, resection of the auricle with its reconstruction, and other operations. The paper discusses the importance of assessing the state of regional lymph nodes in skin melanoma to decide whether to perform lymph node dissection. In addition to adequate excision of primary skin melanoma, to ensure the radicalness of surgical treatment, according to indications, lymph node dissection is performed in case of met astatic lesions of regional lymph nodes. A modern approach to detecting latent metastases involves performing a biopsy of sentinel lymph nodes. The information obtained is extremely important not only in assessing the damage to regional lymph nodes, determin ing the stage of the disease, but also in choosing the tactics of treatment and predicting the course of the tumor. Significant in the work is the conclusion that regional lymph node dissection is performed only in case of met astatic lesions of regional lymph nodes, confirmed morphologically. Accordingly, the best option is to perform regional lymph node dissection simultaneously with excision of primary skin melanoma. Prophylactic lymph node dissection for skin melanoma is not recommended. In conclusion, the latest trends in the surgical treatment of skin melanoma are indicated: an adequate reduction in the indentation and volume of operations when removing primary melanomas, an increase in the role of sentinel lymph node biopsy, the need for morphological verification of lymph node involvement in justifying lymph node dissection, and an increase in the number of metastasectomy.

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SURGICAL ASPECTS TREATMENT OF SKIN MELANOMA (literature review)

Guseynov¹,

Guseynov

Sedov

2023

Clinical Medicine and Pharmacology

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DIAGNOSIS OF SKIN MELANOMA: CURRENT STATUS AND PROSPECTS (literature review)

Guseynov¹,

Guseynov

Sedov

2023

Clinical Medicine and Pharmacology

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The work is devoted to the diagnosis of skin melanoma. The article reflects the main factors affecting the survival of patients. The basic principles of melanoma diagnostics are presented. Methods for diagnosing skin melanoma, including invasive and non-invasive methods, are described in detail and with justification. Of the non-invasive methods for diagnosing skin melanoma, the role of physical examination and dermatoscopy in case of suspected melanoma is emphasized. Of the instrumental methods of examination, the use of such research methods as ultrasound, computed tomography, magnetic resonance imaging, positron emission tomography is con sidered. From laboratory methods, methods of molecular genetic research and determination of skin melanoma biomark ers are presented. Of the invasive methods, the use of biopsy methods such as excisional and incisional biopsy is considered, with specification of indications and contraindications for their use. At the end of the work, the main requirements for the early diagnosis of skin melanoma are listed. In conclusion, the latest trends in the diagnosis of skin melanoma, new non-invasive methods and an algorithm for diagnosing skin melanoma are identified.

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DIAGNOSIS OF MELANOMA: CURRENT STATE AND PROSPECTS (literature review)

Guseynov,

Sedov

2023

Clinical Medicine and Pharmacology

View full text Add to dashboard Cite

The article reflects the main factors influencing the survival of patients. The basic principles of diagnosing melanoma are presented. Methods for diagnosing skin melanoma, including invasive and non-invasive methods, are presented in detail and with justification. Among non-invasive methods for diagnosing skin melanoma, the role of physical examination and dermatoscopy in cases of suspected melanoma is emphasized. Among instrumental examination methods, the use of such research methods as ultrasound, computed tomography, magnetic resonance imaging, positron emission tomography is considered. Among laboratory methods, methods of molecular genetic research and determination of biomarkers of skin melanoma are presented. Among the invasive methods, the use of such biopsy methods as excisional and incisional biopsy is considered, with clarification of the indications and contraindications for their use. At the end of the work, the basic requirements for the early diagnosis of skin melanoma are listed. In conclusion, the latest trends in the diagnosis of skin melanoma, new non-invasive methods and an algorithm for diagnosing skin melanoma are identified.

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Melanoma of the lower female genital tract (vulva, vagina, and cervix): literature review and own cases

Abstract: В статье освещены особенности диагностики, клиническая картина и различные подходы к лечению меланом вульвы, влагалища и шейки матки.

Cited by 5 publications

References 46 publications

SURGICAL ASPECTS TREATMENT OF SKIN MELANOMA (literature review)

SURGICAL ASPECTS TREATMENT OF SKIN MELANOMA (literature review)

DIAGNOSIS OF SKIN MELANOMA: CURRENT STATUS AND PROSPECTS (literature review)

DIAGNOSIS OF MELANOMA: CURRENT STATE AND PROSPECTS (literature review)

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