Melanoma on dysplastic nevus spilus

Grinspan, D; Casalá, A. M.; Abulafia, J; Mascotto, Jorge; Allevato, Miguel

doi:10.1046/j.1365-4362.1997.00076.x

Cited by 24 publications

(28 citation statements)

References 16 publications

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“…We report a case of a malignant melanoma on a NS showing one distinctive characteristic: presence of terminal hairs. To our knowledge this feature was first reported by Grinspan et al 1 . in 1997.…”

Section: Introductionsupporting

confidence: 55%

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Melanoma arising in a hairy nevus spilus

et al. 2006

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Cutaneous melanoma may develop de novo on normal skin or in contiguity with a potential melanocytic precursor. We report a 45-year-old man who presented with a recently developed nodule in a previously stable congenital nevus. Physical examination revealed a 10x18-cm lesion with speckled lentiginous pigmentation and terminal hairs on the lower back. A 2x2-cm suspicious nodule in the lesion was noted by the patient 2 months earlier. Histopathological evaluation of the nevus and the suspicious nodule revealed the characteristics of a melanocytic nevus and melanoma, respectively. It was interesting for the authors to observe terminal hairs in a lesion that was clinically 'speckled lentiginous' in appearance. This case report is a reminder that there may be great variation in the clinical appearance of nevus spilus, and thus dermatologists must be aware of these lesions as potential precursors of malignant melanoma.

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Section: Introductionsupporting

confidence: 55%

“…Prevalence of NS in the population has been reported to be 2.3% and it generally occurs within the first year of life; sometimes between childhood and youth 2 . The speckled dots appear even later, between the ages 6 and 39 years 1,6 . They often range from 1 to 3 mm in diameter but occasionally are larger 6 .…”

Section: Discussionmentioning

confidence: 94%

Melanoma arising in a hairy nevus spilus

et al. 2006

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“…This naevus was surgically removed to rule out the clinical suspicion of CMM 7 . Although naevus spilus cannot be considered a marker of risk for melanoma, malignant degeneration has been reported in 15 cases 8–10 . Therefore, if these naevi change in any way, surgery is recommended to exclude the possibility of a developing CMM.…”

mentioning

confidence: 99%

Spitz naevus arising within congenital naevus spilus

Calista

2004

Acad Dermatol Venereol

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“…Histologically, the tannish macule mostly shows only a mild melanocytic hyperplasia, whereas the small flat spots have features of simple lentigo; the pigmented papules are junctional or compound nevi, but also Spitz nevi or blue nevi can be observed 4,5 . Very few cases have been described of melanoma arising on nevus spilus 6–11 . This case is an additional report of melanoma arising on nevus spilus, with the additional peculiarity of multifocality.…”

Section: Discussionmentioning

confidence: 82%