A new international standard, CIE S 026:2018, defines spectral sensitivity functions that describe optical radiation for its ability to stimulate each of the five α-opic retinal photoreceptor classes that contribute, to non-visual effects and functions of light in humans via intrinsically-photosensitive retinal ganglion cells (ipRGCs). The CIE recently published an α-opic toolbox that calculates all the quantities and ratios of the α-opic metrology in the photometric, radiometric and photon systems, either based on a measured (user-defined) spectrum or on selected illuminants (A, D65, E, FL11, LED-B3) built into the toolbox. For most practical ecologically-valid applications, the melanopsin-based photoreception of ipRGCs has been shown to account for the light sensitivity of non-visual responses, from shifting the timing of nocturnal melatonin secretion to regulating steady-state pupil diameter. A CIE position statement recently adopted melanopic EDI in preliminary guidance on using the “proper light at the proper time” to manipulate non-visual responses. Further guidance in this field is expected from an upcoming scientific consensus paper by the participants of the 2nd International Workshop on Circadian and Neurophysiological Photometry (in Manchester, August 2019). Recent findings continue to confirm that melanopsin also plays a role in visual responses. For instance, brightness perception and aspects of spatial vision can be modulated significantly by melanopsin-based photoreception.The new α-opic metrology standardised in CIE S 026 enables traceable measurements for a formal, quantitative specification of personal light exposures and lighting designs. Here, we apply this metrology, together with the toolbox, to everyday light sources including a natural daylight time series, a range of LED lighting products and a smartphone display screen. This collection of examples is of interest to both lighting and public health professions, and suggests ways in which modulations in the melanopic content of light across time of day can be adopted within strategies that use light to support human health and wellbeing.