Melanotic nasal malignant melanoma - a rare case report

Vinod, S; Hegde, KK

doi:10.4103/0971-3026.32301

Cited by 2 publications

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“…Chemotherapy and radiotherapy have also shown contradictory results. There are only few reports from the Indian sub-continent [1][2][3]. We report a case of melanocarcinoma of sino-nasal region in a 42 year old female who presented with brownishcolored sino-nasal mass involving left orbit, facial swelling on left side and ulceration of overlying skin, cervical and distant metastasis in liver over a short time span of 3 months.…”

Section: Introductionmentioning

confidence: 98%

Mucosal Malignant Melanoma of Sino-Nasal Region with Orbital Involvement: Case Report

Jain

Priya

Kumar³

2012

Indian J Otolaryngol Head Neck Surg

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We report a case of melanocarcinoma of sinonasal region in a 42 year old female who presented with brownish-colored sino-nasal mass involving left orbit, spontaneous epistaxis, facial swelling on left side, and ulceration of overlying skin, cervical and distant metastasis in liver over a short time span of 3 months. On biopsy, the mass was diagnosed as melanocarcinoma of nose and paranasal sinuses. Primary mucosal malignant melanoma of the nasal cavity, paranasal sinuses, and nasopharynx is an aggressive disease and fortunately rare with current research data being mainly from western populations. The disease is known to be more common among elderly population in their seventies and to follow a prolonged course due to innocuous symptoms. This case is being reported for its rarity in our geographical region, early age of presentation and rapid progression of the disease over a span of 3 months.

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Section: Introductionmentioning

confidence: 98%

Mucosal Malignant Melanoma of Sino-Nasal Region with Orbital Involvement: Case Report

Jain

Priya

Kumar³

2012

Indian J Otolaryngol Head Neck Surg

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Primary malignant melanoma at unusual sites: an institutional experience with review of literature

Das

Kumar²,

Ahuja³

et al. 2010

Melanoma Research

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Apart from the skin and choroid plexus, primary malignant melanoma is rare at the other sites and lacks organized documentation. Here, we have tried to enumerate the primary malignant melanomas at various atypical sites, supported by literature review. Seventeen cases were identified from our records of the past 5 years, which had detailed clinical work-up to exclude a possibility of a metastasis. A clear female predominance with involvement of the lower genitourinary tract was identified. In addition to three cases from the vagina, two cases each from the cervix, ovary and urethra, respectively, such cases were also identified in cerebral cortex (frontal and fronto-parietal area), rectum, nasal cavity, tongue, breast and tonsillar fossa. Although many were amelanotic, no specific histology was noted. In conclusion, malignant melanomas can arise in unconventional areas. Gross tumor appearance and the unavailability of an immunohistochemical panel, may result in their misdiagnosis as primary epithelial malignancies. A possible metastasis should always be ruled out.

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Melanotic nasal malignant melanoma - a rare case report

Cited by 2 publications

References 0 publications

Mucosal Malignant Melanoma of Sino-Nasal Region with Orbital Involvement: Case Report

Mucosal Malignant Melanoma of Sino-Nasal Region with Orbital Involvement: Case Report

Primary malignant melanoma at unusual sites: an institutional experience with review of literature

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