Melaphen, malamine, and bis(hydroxymethyl)phosphinic acid. Acid-base properties and behavior in the presence of some metal cations

Sal'nikov, Yu. I.; Boos, G. A.; Рыжкина, И. С.; Фаттахов, С. Г.; Чмутова, Г. А.; Zaripova, G. R.

doi:10.1134/s107036320906005x

Cited by 3 publications

(2 citation statements)

References 4 publications

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“…1). Based on the acid-base equilibria constants reported by Sal'nikov et al, 26 only M is present at pH greater than 7 and MH + is the predominant species between pH 2 and 6, as shown in Fig. S1 in the ESI † where the stability region for the different protonated species (MH + ), (MH 2…”

Section: Melamine Adsorption Determinationmentioning

confidence: 95%

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Melamine adsorption on carbon materials: impact of carbon texture and surface chemistry

et al. 2020

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Section: Melamine Adsorption Determinationmentioning

confidence: 95%

“…) and (M 2 H + ) that can form are summarized. 26,27 To confirm the speciation diagram for melamine accurately describes the speciation in solution as a function of pH, mainly in acid media, the changes in the UV-visible absorption spectrum of melamine were also investigated. As shown in Fig.…”

Section: +mentioning

confidence: 99%

Melamine adsorption on carbon materials: impact of carbon texture and surface chemistry

et al. 2020

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Hydrogen's isotopic exchange reaction in the C‐methyl sides in the medicinal agent xymedon: NMR spectroscopy and ab initio calculations

Latypov

Kondrashova

Galyametdinova

et al. 2018

J of Physical Organic Chem

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The kinetics of intramolecular and intermolecular exchange processes in xymedon (1‐(2‐hydroxyethyl)‐4,6‐dimethyl‐1,2‐dihydropyrimidin‐2‐one, a regeneratory, wound‐healing drug) and its analogue were investigated in the solution. Hydrogen's mobility was detected in the C‐methyl sides of these compounds. This mobility was monitored via NMR in the hydrogen/deuterium exchange reaction in water. Two models were proposed as explanations for this hydrogen‐deuterium exchange. According to the main model, the key intermediates of these reactions are low‐energy tautomers of xymedon in which the N3 is protonated following which one proton leaves either 6‐Me or 4‐Me and thus its hybridization is changed. This hydrogen‐to‐deuterium exchange reaction is much faster under acidic conditions although it also occurs in alkaline conditions. Methylation via MeOTs or MeI leads to products with a quaternized ring N3 atom in which a hydrogen‐to‐deuterium exchange reaction also takes place, although the rates of the 6‐Me and 4‐Me hydrogens exchange are reversed. According to density functional theory calculations, the presence of methyl groups at the C4/C6 positions and of the C═O fragment is crucial to remarkably lower the energies of these “rare” tautomers. The exact position of the C═O in heterocycle is also very important in the tautomers' relative stability.

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Pilot-scale removal of persistent and mobile organic substances in granular activated carbon filters and experimental predictability at lab-scale

Schumann

Müller

Eckardt

et al. 2023

Science of The Total Environment

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Melaphen, malamine, and bis(hydroxymethyl)phosphinic acid. Acid-base properties and behavior in the presence of some metal cations

Cited by 3 publications

References 4 publications

Melamine adsorption on carbon materials: impact of carbon texture and surface chemistry

Melamine adsorption on carbon materials: impact of carbon texture and surface chemistry

Hydrogen's isotopic exchange reaction in the C‐methyl sides in the medicinal agent xymedon: NMR spectroscopy and ab initio calculations

Pilot-scale removal of persistent and mobile organic substances in granular activated carbon filters and experimental predictability at lab-scale

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