Melatonin: A new bioactive compound in wine

Rodriguez-Naranjo, M. Isabel; Gil‐Izquierdo, Ángel; Troncoso, Ana M.; Cantos, Emma; García‐Parrilla, M. Carmen

doi:10.1016/j.jfca.2010.12.009

Cited by 105 publications

(125 citation statements)

References 25 publications

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“…The HPLC apparatus used was a Varian ProStar 210 (Palo Alto, CA, USA) equipped with a fluorimeter (821-FP, Jasco, Japan spectroscopic Co. Ltd., Tokyo, Japan) recording wavelengths of 285 nm for excitation and 345 nm for emission [28,29] and a reverse phase column (Kinetex, 5 µm particle, 150 × 4.6 mm, 100 Å, Phenomenex Inc., Torrance, CA, USA) set at 25 • C and preceded by a SecurityGuard ULTRA guard cartridge (UHPLC C18, Phenomenex Inc., Torrance, CA, USA). Chromatographic separation was performed using a binary gradient consisting of (A) aqueous formic acid (0.1% v/v), and (B) methanol.…”

Section: Analysis Of Melatoninmentioning

confidence: 99%

Impact of Saccharomyces cerevisiae Strains on Health-Promoting Compounds in Wine

et al. 2018

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Abstract:Moderate wine consumption is associated with human health benefits (reduction of cardiovascular risk and neurodegenerative diseases, decrease of onset of certain cancers) attributed to a series of bioactive compounds, mainly polyphenols, with antioxidant power capable of counteracting the negative action of free radicals. Polyphenols are naturally present in the grapes, but an additional amount originates during winemaking. The aim of this work was to assess the ability of four commercial and two indigenous Saccharomyces cerevisiae strains to produce bioactive compounds (tyrosol, hydroxytyrosol, tryptophol, melatonin and glutathione) during alcoholic fermentation. In order to exclude the fraction of antioxidant compounds naturally occurring in grapes, the strains were inoculated in a synthetic must. At the end of fermentation the bioactive compounds were analysed by High-Performance Liquid Chromatography, while antioxidant activity was measured by 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay. Moreover, freeze-dried samples, originating from the experimental wines, were used to perform ex-vivo assays on cultured cells (RAW 264.7 murine macrophages) with the aim to evaluate their antioxidant and anti-inflammatory activities. The results indicated that the production of the considered bioactive compounds is a strain-specific property; therefore, the different yeast strains utilized during fermentation have different capabilities to modify the antioxidant and anti-inflammatory properties of the wine.

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Section: Analysis Of Melatoninmentioning

confidence: 99%

Impact of Saccharomyces cerevisiae Strains on Health-Promoting Compounds in Wine

et al. 2018

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“…맥주와 와인과 같은 음료 (Maldonado et al, 2009;Rodriguez-Naranjo et al, 2011a;Gomez et al, 2012)에서 멜라토닌을 확인하기 위해 많은 연구가 수행되었다 (Dubbels et al, 1995;Hattori et al, 1995). 포도에서 보고된 멜라토닌의 농도는 Cabernet Franc (Iriti et al, 2006) 0.005 ng/g에서 Merlot (Murch et al, 2010) …”

Section: 미생물의 멜라토닌 합성unclassified

The Potential of Melatonin for the Application in Dairy Products

Song¹,

Park²,

Yoo³

et al. 2018

J. Milk Sci. Biotechnol.

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“…Many studies have previously reported that melatonin was clearly separable from other potentially interfering indoleamines with HPLC-FD [15][16][17][18][19][20]. The extraction/purification step with solid phase extraction (SPE) further reduced the likelihood of interfering compounds.…”

Section: Melatonin Analysis By Hplcmentioning

confidence: 99%

“…The extraction/purification step with solid phase extraction (SPE) further reduced the likelihood of interfering compounds. Previous studies [16,17] validated the HPLC-FD method as reliable for the quantitative analysis of melatonin and met Association of Official Agricultural Chemists (AOAC) requirements compared to LC-MS.…”

Section: Melatonin Analysis By Hplcmentioning

confidence: 99%

Determination of melatonin content in traditional Thai herbal remedies used as sleeping aids

Padumanonda¹,

Johns²

2013

Planta Med

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Background: Melatonin content was screened in leaves of seven edible herbs used as sleeping aids in Thai traditional medicine. These plants are Piper nigrum L, Sesbania glandiflora (L.) Desv., Sesbania sesban (L.) Merr., Senna tora (L.) Roxb., Moringa oleifera Lam., Momordica charantia L. and Baccaurea ramiflora Lour. Dried leaves were extracted by sonication in methanol for six hours at room temperature, and then melatonin was purified by C18 solid phase extraction (SPE). Melatonin was then quantified by a validated RP-C18 HPLC method with fluorescent detection.

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Melatonin: A new bioactive compound in wine

Cited by 105 publications

References 25 publications

Impact of Saccharomyces cerevisiae Strains on Health-Promoting Compounds in Wine

Impact of Saccharomyces cerevisiae Strains on Health-Promoting Compounds in Wine

The Potential of Melatonin for the Application in Dairy Products

Determination of melatonin content in traditional Thai herbal remedies used as sleeping aids

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