Melatonin Reshapes Olive Oil Properties in Response to Different Rates of Irrigation

Gholami, Rahmatollah; Hoveizeh, Narjes Fahadi; Zahedi, Seyed Morteza; Carillo, Petronia

doi:10.1007/s00344-022-10856-2

Cited by 1 publication

(1 citation statement)

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“…The crucial role of the interaction between lipophilic antioxidants and lipid bilayers in stabilizing biological membranes and their components from oxidative damage has been extensively studied and reviewed [61]. In this context, it has been reported that the modification of biophysical properties of the lipid bilayer (decreased membrane fluidity) is one of the main mechanisms underlying the antimicrobial, antiplatelet and anti-proliferative effects of DAS [62][63][64][65].…”

Section: Discussionmentioning

confidence: 99%

Improving the anti-diabetic and anti-hyperlipidemic activities of extra virgin olive oil by the incorporation of diallyl sulfide

Emna Habibi,

Tarek Baâti,

Slimen Selmi

et al. 2024

Cell Mol Biol (Noisy-le-grand)

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Development of novel functional foods is trending as one of the hot topics in food science and food/beverage industries. In the present study, the anti-diabetic, anti-hyperlipidemic and histo-protective effects of the extra virgin olive oil (EVOO) enriched with the organosulfur diallyl sulfide (DAS) (DAS-rich EVOO) were evaluated in alloxan-induced diabetic mice. The ingestion of EVOO (500µL daily for two weeks) attenuated alloxan-induced elevated glucose, alanine transaminase (ALT), aspartate transaminase (AST), alkaline phosphatase, lactate dehydrogenase (LDH), urea and creatinine. It also normalized the levels of triglycerides (TG), total cholesterols (TC), low-density lipoprotein-cholesterol (LDL-c) and their consequent atherogenic index of plasma (AIP) in diabetic animals. Additionally, EVOO prevented lipid peroxidation (MDA) and reduced the level of hydrogen peroxide (H2O2) in diabetic animals. Concomitantly, it enhanced the activity of the antioxidant enzymes catalase (CAT), glutathione peroxidase (GPx) and superoxide dismutase (SOD), reducing thereby tissue oxidative stress injury. The overall histologic (pancreas, liver, and kidney) alterations were also improved after EVOO ingestion. The manifest anti-diabetic, lipid-lowering and histo-protective properties of EVOO were markedly potentiated with DAS-rich EVOO suggesting possible synergistic interactions between DAS and EVOO lipophilic bioactive ingredients. Overall, EVOO and DAS-rich EVOO show promise as functional foods and/or adjuvants for the treatment of diabetes and its complications.

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Section: Discussionmentioning

confidence: 99%