2015
DOI: 10.1016/j.rmcr.2014.12.005
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Melioidosis mycotic aneurysm: An uncommon complication of an uncommon disease

Abstract: Melioidosis is often considered an exotic and uncommon disease in most parts of the world. However it is an endemic disease in Southeast Asia and Northern Australia with an expanding distribution. Melioidosis can involve almost any organ and can deteriorate rapidly. In this report, we describe a rapidly fatal case of a mycotic aneurysm associated with melioidosis despite aggressive antibiotic therapy. The morbidity and mortality of this uncommon complication remains high despite prompt diagnosis and treatment.… Show more

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Cited by 9 publications
(14 citation statements)
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“…It is documented that most patients with infected mycotic aneurysm secondary to melioidosis are male and aged 60 years [1,2,12,19]. Similarly, in our case series, the ages of eight subjects ranged from 48 to 69, with a median age of 61.5 years, all were indigenous males, and two [24], Case 12-14 [25], Case 15 [26], Case 16 [3], Case 17 [27], Case 18 [28], Case 19 [29], Case 20 [30], Case 21 [31], Case 22 [19], Case 23-24 [6], and Case 25-26 [10], Case 27 [52], Case 28 [18], Case 29 [32], Case 30 [33], Case 31 [41], Case 32 [35], Case 33 [36], Case 34 [8] Case 35 [37], Case36 [38], Case37 [39], and Case38 [40].…”
Section: Discussionsupporting
confidence: 61%
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“…It is documented that most patients with infected mycotic aneurysm secondary to melioidosis are male and aged 60 years [1,2,12,19]. Similarly, in our case series, the ages of eight subjects ranged from 48 to 69, with a median age of 61.5 years, all were indigenous males, and two [24], Case 12-14 [25], Case 15 [26], Case 16 [3], Case 17 [27], Case 18 [28], Case 19 [29], Case 20 [30], Case 21 [31], Case 22 [19], Case 23-24 [6], and Case 25-26 [10], Case 27 [52], Case 28 [18], Case 29 [32], Case 30 [33], Case 31 [41], Case 32 [35], Case 33 [36], Case 34 [8] Case 35 [37], Case36 [38], Case37 [39], and Case38 [40].…”
Section: Discussionsupporting
confidence: 61%
“…In addition, it should be noted that 5% represents PLOS NEGLECTED TROPICAL DISEASES the proportion of aneurysms in bacteremic melioidosis cases and the overall proportion for all melioidosis cases should be around half that. The increasing articles in the literature have reported the epidemiological data of mycotic aneurysm secondary to melioidosis in various regions [1,3,6,12]. Our literature review showed that the incidence of mycotic aneurysm caused by B. pseudomallei was geographically varied, for example, 0.4% (2 of 540 cases of melioidosis) in Australia [13] and 7.5% in Malaysia (5 of 67 cases of melioidosis 1975 to 2015) [11,45].…”
Section: Discussionmentioning
confidence: 72%
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“…Involvement of the cardiovascular system, a rare occurrence associated with high morbidity and relapse rates, has also been observed in melioidosis cases in Singapore [ 24 ]. Rao et al (2009) [ 25 ] reported two cases presenting with abdominal aortic pseudo-aneurysms requiring both medical and surgical intervention, with only one surviving.…”
Section: Clinical Aspectsmentioning
confidence: 99%
“…Melioidosis can have 2 major presentations; acute infection (symptoms lasting less than 2 months) and chronic infections (symptoms lasting more than 2 months) [ 8 , 12 , 16 ]. Melioidosis can present as septicemia, localized infection with/without septicemia, asymptomatic infections, ulcers, pneumonia,visceral abscesses, neurologic infection, musculoskeletal infections [ 6 , 8 , 9 ].…”
Section: Discussionmentioning
confidence: 99%