The mixing and processing of high-viscosity materials play a pivotal role in composite material processing. In this context, the internal meshing screw mixer, rooted in volume extensional rheology, offers distinct advantages, including heightened mixing efficiency, exceptional material adaptability, and favorable thermomechanical properties. This research endeavors to advance our understanding of these qualities by presenting an in-depth exploration of internal meshing screw mixing. To facilitate this, an internal meshing screw mixing experimental apparatus was meticulously constructed, accompanied by extensive numerical simulations and experimental investigations into its heat transfer characteristics. Two distinct heat transfer modes are established: Mode 1 entails the transfer of the high temperature from the outer wall of the stator to the interior, while Mode 2 involves the transmission of the high temperature from the inner wall of the rotor to the exterior. The ensuing research yields several notable findings: 1. It is evident that higher rotational speeds lead to enhanced heat transfer efficiency across the board. However, among the three rotational speeds examined, 60 rpm emerges as the optimal parameter for achieving the highest heat transfer efficiency. Furthermore, within this parameter, the heat transfer efficiency is superior in Mode 1 compared to Mode 2. 2. As eccentricity increases, a corresponding decline in comprehensive heat transfer efficiency is observed. Moreover, the impact of eccentricity on heat transfer efficiency becomes increasingly pronounced over time. 3. A lower gap dimension contributes to higher heat transfer within the system. Nevertheless, this heightened heat transfer comes at the expense of reduced stability in the heat transfer process. 4. It is demonstrated that heat transfer in Mode 1 primarily follows a convection heat transfer mechanism, while Mode 2 predominantly exhibits diffusion-based heat transfer. The heat transfer efficiency of Mode 1 significantly surpasses that of Mode 2. This research substantiates its findings with the potential to enhance the heat transfer efficiency of internal meshing screw mixers, thereby making a valuable contribution to the field of polymer engineering and science.