Members of the family <i>Lamiaceae</i> Lindl. as sources of medicinal plant raw materials to obtain neurotropic drugs

Abstract

The aim of this work is to review and analyze the data published in the modern scientific literature obtained in pharmacological, pharmacognostic and pharmacotechnological studies of various types of raw materials obtained from members of the family Lamiaceae L., which were sources of biologically active substances, pharmaceutical substances, total extracts and the drugs – with a neurotropic activity.Materials and methods. For the review, we used the information of scientific literature from open and accessible sources of the last twenty years, located in the scientific and technical libraries of institutions, as well as in electronic databases: Elibrary, PubMed, Scopus, Cyberleninka, GoogleAcademy, J-Stage. The search inquiries were: the species of the family Lamiaceae (Russian and Latin), the samples of medicinal plant materials based on them as well as the names of the drugs and biologically active substances obtained from these raw materials.Results. When working with the sources of scientific information, the main attention was paid to pharmacologic tests performed during the studies on laboratory animals and proving the presence of neurotropic activity in the studied objects – essential oils and extracts from plant raw materials: aqueous, aqueous alcoholic, and methanol ones. It has been established that the potential of the therapeutic and preventive application of pharmaceutical substances and drugs based on the medicinal plant materials obtained from 30 genera members of the Lamiaceae family, remains unrealized despite the close attention of various researchers.Conclusion. This review comprised 71 species from 30 genera. Despite the significant level of the previous study presented in the analysis of this publication, an enormous potential of this family’s species remains unexplored. In the future, they can be of both – pharmacognostic and practical interest, in particular, in creation of new medicinal preparations of the neurotropic action based on them.

Hyssopus Essential Oil: An Update of Its Phytochemistry, Biological Activities, and Safety Profile

“…The essential oil and the extracts isolated from plants demonstrated average in vitro antibacterial activity, antimycotic insect killing, and antiviral properties [ 52 , 53 ]. Hyssop essential oil extracts showed excellent antioxidant and anticancer activities [ 28 , 54 ], although there is significant potential that has yet to be investigated [ 55 , 56 ].…”

Phytochemical Analysis, Antioxidant and Anticancer Potential of Sideritis niveotomentosa: Endemic Wild Species of Turkey

“…Turkey, home to 11,707 plant taxa, including endemic 3649 [ 3 ], is a key country for the protection of global biodiversity in Anatolia because of its complex topography, geomorphology, and location. Among the official plants, the Lamiaceae family contains extremely interesting examples offering natural ingredients and high-quality raw materials [ 4 ]. The Lamiaceae family consists of approximately 220 genera and 7000 species worldwide [ 5 ].…”

Influence of Lavandula angustifolia, Melissa officinalis and Vitex angus-castus on the organism of rats fed with excessive fat-containing diet

“…Most often, for those purposes, the treatment involves plants of Lamiaceae family (Michel et al, 2020). Zvezdina et al (2020) have made a review of 71 species from 30 genera of Lamiaceae family, and drew the conclusion that the immense potential of plants of this family is still unexplored. These valuable medicinal plants could help in development of neurotropic preparations.…”