2001
DOI: 10.1016/s0958-1669(00)00201-9
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Membrane separations in biotechnology

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Cited by 384 publications
(165 citation statements)
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“…[1][2][3] Despite possessing many desirable mechanical and chemical properties, polyarylsulfones are relatively hydrophobic, and membranes produced using these polymers can therefore be prone to fouling. Fouling is one of the most detrimental problems encountered in membrane associated processes, since it can result in higher energy demands, shorter membrane lifetime, unpredictable performance or product contamination.…”
Section: Introductionmentioning
confidence: 99%
“…[1][2][3] Despite possessing many desirable mechanical and chemical properties, polyarylsulfones are relatively hydrophobic, and membranes produced using these polymers can therefore be prone to fouling. Fouling is one of the most detrimental problems encountered in membrane associated processes, since it can result in higher energy demands, shorter membrane lifetime, unpredictable performance or product contamination.…”
Section: Introductionmentioning
confidence: 99%
“…Filtration-based techniques present problems of filter fouling after a relatively short period of operation (Kawahara et al 1994;Van Reis and Zydney 2001). Centrifuges may suffer from cell adhesion and clogging, besides their high mechanical complexity and high cost (Jäger 1992;Tokashiki et al 1990).…”
Section: Introductionmentioning
confidence: 99%
“…Usually, thickness is on the order of 100 -200 µm both to provide mechanical stability as well as to obtain the required filtration properties through the joint effect of the micro-or nanoporous polymer mesh making up the membrane. However, particularly for very small pore sizes, fluidic resistance of these membranes become exceedingly high thus limiting flux and ultimately the productivity of the filtration process (DiLeo, Allegrezza et al 1992;van Reis & Zydney 2001). In contrast, a membrane manufactured by a combination of NSL and plasma etching technology should exhibit much larger flux and possibly a narrower pore size distribution.…”
Section: Filter Membranesmentioning
confidence: 99%