Membranous Lipodystrophy‐Like Changes in Two Cases of Traumatic Lipogranuloma Caused by Safety Belts

Abstract

A few cases of subcutaneous nodules with the histological findings of membranous lipodystrophy-like changes have been reported in the literature. However, reports of membranous lipodystrophy-like changes caused by trauma are exceedingly rare. We report two cases of traumatic lipogranuloma that had linear and multiple lesions showing membranous lipodystrophy-like changes and were induced by safety belt trauma after a car accident. These patients showed peculiar changes in their subcutaneous fat and had linear patterned, multiple, nodular lesions with membranous lipodystrophy-like changes caused by trauma.

Membranous lipodystrophy: case report and review of the literature

“…Several clinical presentations comprising tender or nontender nodules, ulcerated or atrophic plaques, depressed lesions, diffuse swelling, and ecchymotic lesions may occur. 6 Our patient had tender, indurated plaques suggesting panniculitis, probably erythema nodosum or thrombophlebitis. The condition can only be diagnosed histopathologically by the presence of multiple, variably sized cysts in the panniculus, lined by an amorphous, homogeneous, eosinophilic membrane.…”

Sterile traumatic panniculitis in a captive Brent goose

“…Nodular changes in subcutaneous fat have been reported following trauma in humans and companion animals, although infrequently, and are considered likely underdiagnosed in cats and dogs. 3,4 Obese cats and dogs are considered more likely to develop traumatic panniculitis, 3 and the high amount of subcutaneous fat in the goose in our case might have predisposed the bird to such lesions. Fat necrosis and panniculitis secondary to trauma are also a common feature of lipomas in companion animals.…”

“…To our knowledge, sterile traumatic panniculitis has not been reported in species other than humans, cats, and dogs. 3,4 An adult female Brent goose (Branta bernicla) from a captive flock was referred to the Exotic Animal Clinic of the Université de Montréal for nodular skin lesions over the head and neck. Although there was no information available regarding the onset and growth pattern of the lesions, the owner reported the bird's feathers had been severely picked in this area by its mate during the breeding season a few months prior to presentation.On physical examination, the animal was in good body condition, and firm, pink skin nodules of 0.5-2.5 cm diameter were present over the head and neck (Fig.…”

Nodular cystic fat necrosis with lipomembranous change observed in splinter granuloma

“… 7 proposed seven hypothetical pathological mechanisms: (i) idiopathic processes; (ii) enormous proliferation of fat cell membranes; (iii) physiochemical interaction between the ground substance in connective tissue and fat droplets; (iv) free fatty acids released from degenerated fat cells processed by macrophages to produce membranous lipodystrophy; (v) a metabolic disorder of lipids in mesenchymal cells; (vi) loops and folds in the basal laminae of fat cells in varying stages of lipid depletion at the time of necrosis; and (vii) ischemic injury of adipose tissue resulting from venous insufficiency. Moreover, repeated trauma or irritation has been proposed as one of the etiological factors in lipomembranous change 8 . Lee et al.…”

“…Lee et al. 8 reported two cases of membranous lipodystrophy‐like changes in traumatic lipogranulomas caused by safety belts. Poppiti et al.…”