Internet memes are an integral part of social media communication and a popular genre for humorous engagement in online political discourses. A meme is a collective of multimodal signs that refer to each other through shared formal, content-related, and/or stance-related characteristics and can be recontextualized on different levels: (1) language, (2) mode of presentation, and (3) humor. In this paper, we examine the perceptions and effects of recontextualization in image macros—the most prominent meme subgenre. Two between-subjects online experiments from Austria offer a holistic approach to meaning-making through multimodal recontextualization in political image macros. The first experiment explored the perception of language variety and its effects on users' intentions to forward a humorous image macro. The second experiment further investigated the effects of a political message's language variety, mode of presentation, and humor on users' perceptions and behavioral intentions. The experiments' results indicate that perceptions and behavioral intentions are mainly affected by a political message's presentation as an image macro, while the recontextualization of language variety and humor plays a minor role. The study contributes to the growing body of knowledge on Internet memes as multimodal and recontextualizable political messages from the receivers' point of view.