This article analyzes the link between the waves of the Nomadic populations settlement and deautochtonization basing our study on the indegenous Mbororo people of Cameroon. These waves of settlement, imposed by a combination of global and local factors, are accompanied by territorial and identity mutation and social renegotiations of access to political citizenship. From a legal status of indigenous people recognized by the UN, we are witnessing a process of disindigenisation. Based on the theory of coloniality and documentary analysis, the results reveal that the deautochtonization of the Mbororos is a consolidated and long-lasting trajectory. In this way, it establishes a new theoretical perspective on indigenous people.