This study aimed to explore the relationship between factual autonomy (FA), organizational citizenship behaviour (OCB) and Counterproductive work behaviour (CWB) in industry workers, possibly mediated by burnout. Participants included 600 industry workers (300 from local and 300 from multinational industries), age 25 through 40 years, with a minimum experience of one year of working on the same position. Organizational Citizenship Behavior Checklist (OCB-C), Factual Autonomy Scale (FAS), Counterproductive Work Behavior Checklist (CWB-C), and Shirom-Melamed Burnout Measure (SMBM) were used to collect data from the participants. The results indicated that, more FA is likely to result in significantly more OCB, significantly lesser CWB and significantly lesser burnout in industry workers. Similarly, an increase in burnout is likely to predict a significant decrease in OCB and significant increase in CWB of industry workers. Further, burnout significantly mediated the relationship between FA and OCB as well as FA and CWB. In a rapidly changing post-covid world, such studies are very important to inform policy makers and have important implications for industrial/organizational psychologists and consultants like defining the limit of autonomy for industry workers, keeping a check on burnout and CWB while striving for more OCB.