Memory-Enhancing and Memory-Related Beneficial Effects of Selected Medicinal Plants from the Nigerian Flora

Elufioye, Taiwo O.

doi:10.1007/978-981-10-5978-0_15

Cited by 1 publication

(1 citation statement)

References 48 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Similarly, the methylene chloride: methanol (1:1; v/v) extract at a single concentration of 200 μg/ml exhibited 36.02 ± 0.18% AChE inhibitory activity with >200 μg/ml, IC 50 value compared to galantamine (100 μg/ml; IC 50 value 24.65 ± 2.12 μg/ml); a standard drug ( Ndam Ngoungoure et al, 2019 ). Elufioye (2017) investigated the effects of various extracts (hexane, ethyl acetate, and aqueous) obtained from A. laxiflora leaves, stem bark, and root bark in inhibiting both AChE and BuChE. The results reported that the A. laxiflora stem bark and root bark extracts showed selective AChE inhibitory activity with percent inhibition ranging from 10.69% to 34.20% ( Table 4 ).…”

Section: Pharmacological Activitymentioning

confidence: 99%

Appraising the therapeutical potentials of Alchornea laxiflora (Benth.) Pax & K. Hoffm., an underexplored medicinal herb: A systematic review

et al. 2022

View full text Add to dashboard Cite

Ethnopharmacological relevance:Alchornea laxiflora (Benth.) Pax & K. Hoffm. (Euphorbiaceae) is an important traditional medicinal plant grown in tropical Africa. The stem, leaves, and root have been widely used in the folk medicine systems in Nigeria, Cameroon, South Africa, and Ghana to treat various ailments, including inflammatory, infectious, and central nervous system disorders, such as anxiety and epilepsy.Material and methods: The scientific name of the plant was validated using the “The Plant List,” “Kew Royal Botanic Gardens,” and Tropicos Nomenclatural databases. The literature search on A. laxiflora was performed using electronic search engines and databases such as Google scholar, ScienceDirect, PubMed, AJOL, Scopus, and Mendeley.Results: To the best of our knowledge, no specific and detailed review has been reported on A. laxiflora. Consequently, this review provides an up-to-date systematic presentation on ethnobotany, phytoconstituents, pharmacological activities, and toxicity profiles of A. laxiflora. Phytochemical investigations disclosed the presence of important compounds, such as alkaloids, flavonoids, phenolics, terpenoids, and fatty acids. Furthermore, various pharmacological activities and traditional uses reported for this botanical drug were discussed comprehensively.Conclusion: This systemic review presents the current status and perspectives of A. laxiflora as a potential therapeutic modality that would assist future researchers in exploring this African botanical drug as a source of novel drug candidates for varied diseases.

show abstract

Section: Pharmacological Activitymentioning

confidence: 99%