Memory for faces in epileptic children before and after brain surgery

Beardsworth, Elizabeth D.; Zaidel, Dahlia W.

doi:10.1080/01688639408402670

Cited by 69 publications

(50 citation statements)

References 17 publications

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“…While some show no change, 4,45 others show improvement in scores after hemispherectomy. 5,38,39,58 The presurgical developmental level seems to be important not only for the capacity of the brain to improve, 2 but also for seizure outcome. 60 Again, patients with severe cortical dysplasia or hemimegencephaly consistently show worse postsurgical outcomes than do those with other etiologies.…”

Section: Neurosurg Focus / Volume 25 / September 2008mentioning

confidence: 99%

Hemispherotomy and other disconnective techniques

Ribaupierre

Delalande

2008

FOC

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The surgical treatment of intractable epilepsy has evolved as new technical innovations have been made. Hemispherotomy techniques have been developed to replace hemispherectomy in order to reduce the complication rates while maintaining good seizure control. Disconnective procedures are based on the interruption of the epileptic network rather than the removal of the epileptogenic zone. They can be applied to hemispheric pathologies, leading to hemispherotomy, but they can also be applied to posterior quadrant epilepsies, or hypothalamic hamartomas. In this paper, the authors review the literature, present an overview of the historical background, and discuss the different techniques along with their outcomes and complications.

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Section: Neurosurg Focus / Volume 25 / September 2008mentioning

confidence: 99%

Hemispherotomy and other disconnective techniques

Ribaupierre

Delalande

2008

FOC

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“…[3][4][5][6] of the block-design test of the German Wechsler Intelligence Scale for Adults (HAWIE) (29). A total score was computed by adding the four raw scores.…”

Section: Visuoconstructive Abilitiesmentioning

confidence: 99%

“…In contrast, Adams et al (2) found significantly decreased verbal memory performance in the left TLE group 6 months after surgery. Referring to an overlapping sample with Adams et al patients, Beardsworth and Zaidel (3) reported improved memory for faces in children who underwent right TLR. Thus the findings of Adams et al and Beardsworth et al seem to correspond to those reported on adults who underwent TLR, emphasizing the risk of memory decline after resection of the dominant temporal lobe (1 1-15).…”

mentioning

confidence: 99%

Pre‐ and Postoperative Neuropsychological Profiles in Children and Adolescents with Temporal Lobe Epilepsy

Lendt¹,

Helmstaedter²,

Elger³

1999

Epilepsia

125

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Summary: Purpose:To evaluate the neuropsychological performance of children before and after temporal lobe resection (TLR).Methods: Memory, attention, language, and visuoconstructive abilities were examined in 20 children (age 10-16 years) before, and 3 and 12 months after TLR (right, n = 10; left, n = 10; two-thirds anterior resection, n = 16; amygdalohippocampectomy, n = 4). Preoperative performance was compared with data of 30 age-matched healthy children; changes in performance after surgery were determined by repeatedmeasurement multivariate analysis of variance (MANOVA) and by use of reliable change indices (RCI).Results: Preoperatively, no differences were observed between patients and controls in verbal and figural memory performance. Children with temporal lobe epilepsy (TLE), however, and particularly those with a left temporal focus, showed significantly reduced language performance. Repeatedmeasurement statistics indicated that memory performance did not change after surgery, whereas language performance and attention significantly improved 3 months and 1 year after surgery, respectively. Individual evaluations of memory showed gains in five children and deterioration in four children. Poor seizure control appeared the decisive variable characterizing children with losses in memory.Conclusions: Compared with adults, pre-and postoperative memory data suggest less pronounced hemispheric differences in school-age children with TLE. The results raise the possibility that children have a lower risk of memory deterioration after TLR, which may be due to their larger potential for cerebral plasticity.

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“…[1,5,11,26,31,61] Important considerations that have contributed to this trend were the appreciation of the adverse effects of seizures on the developing brain, the plasticity of the young brain in response to surgery, and the hope of some developmental "catch up" after successful early surgical treatment. [8,9,54] However, the natural history of epilepsy in childhood is not yet very well known. Thus, selection criteria for epilepsy surgery remain incompletely defined, partly because of an existing historical belief that children may grow out of their epilepsy.…”

mentioning

confidence: 99%

Surgery in epilepsy associated with focal lesions in childhood

Bourgeois¹,

Sainte‐Rose²,

Lellouch‐Tubiana³

et al. 1999

FOC

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Surgery in children with epilepsy is a new, evolving field. The important practical issues have been to define strategies for choosing the most suitable candidates, as well as the type and the optimum timing of epilepsy surgery. This study was undertaken to illustrate these points. To identify the factors that correlated with outcome, the authors analyzed a series of 200 children (aged 1–15 years, mean 8.7 years) who underwent surgery at the Hôpital Necker-Enfants Malades between 1981 and 1996. In 171 cases (85.5%) the epilepsy was medically refractory and was associated with focal cortical lesions. Surgery consisted of resection of the lesion without specifically attempting to identify and remove the "epileptogenic area." In the group of children whose seizures were medically refractory, the mean follow-up period was 5.8 years. According to Engel's classification, 71.3% of these children became seizure free (Ia), whereas 82% were in Class I. A multivariate statistical analysis revealed that among all the factors studied, the success of surgery in a patient in whom there was a good clinical-electroencephalogram-imaging correlation, depended on the patients' having undergone a minimally traumatic operation, a complete resection of the lesion, and a short preoperative seizure duration. After the surgical control of epilepsy, behavior disorders were more improved (31% of all patients) than cognitive function (25%). The patient age at onset, duration and frequency of seizures, intractability of the disease to therapy, and seizure characteristics, were correlated with cognitive, behavioral, and academic performance pre- and postoperatively. Multivariate statistical analysis revealed that cognitive dysfunction correlated highly with the duration of epilepsy prior to surgery, whereas behavioral disorders correlated more with seizure frequency. These data must be taken into account when selecting patients for surgical treatment and when deciding the timing of surgery. Early surgical intervention allows for optimum brain development.

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Memory for faces in epileptic children before and after brain surgery

Cited by 69 publications

References 17 publications

Hemispherotomy and other disconnective techniques

Hemispherotomy and other disconnective techniques

Pre‐ and Postoperative Neuropsychological Profiles in Children and Adolescents with Temporal Lobe Epilepsy

Surgery in epilepsy associated with focal lesions in childhood

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