Encyclopedia of Life Sciences 2009
DOI: 10.1002/9780470015902.a0021398
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Memory: Mechanisms Other than LTP

Abstract: Synaptic plasticity is not the exclusive mode of memory storage, and persistent regulation of voltage‐gated ionic channels also participates in information storage. Long‐term changes in neuronal excitability have been reported in several brain areas following learning. Synaptic activation of glutamate receptors initiates long‐lasting modification in neuronal excitability at the pre‐ or postsynaptic side. Intrinsic plasticity is mediated by changes in the expression level or biophysical properties of ion channe… Show more

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