“…73–85 The nanofabrication technologies for preparing SEIRA/SERS substrates include chemical preparation methods, photolithography, electron beam lithography, magnetron sputtering, electron beam evaporation, and more. 86–107 The widely used theory for modeling SERS/SEIRA includes perturbation theory, 108 temporal coupled-mode theory, 109,110 coupled harmonic oscillator theory, 111 and so on. As mentioned earlier, machine learning is complementary to SERS/SEIRA and offers unparalleled possibilities for solving pressing challenges related to spectral artifacts, overlapping, and huge volumes of spectral data (Fig.…”