Men’s attitudes regarding genetic testing for hereditary prostate cancer risk

Miesfeldt, Susan; Jones, Susan; Cohn, Wendy F.; Lippert, Marguerite C.; Haden, Kathleen; Turner, B.; Martin-Fries, Tracee; Clark, S. Michael

doi:10.1016/s0090-4295(99)00400-8

Cited by 35 publications

(26 citation statements)

References 30 publications

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“…This is consistent with the high levels reported in many other studies of genetic testing for a range of common conditions, including 60% for lung cancer [8], as well as 20–96% (mean 66%) for breast cancer [5], 74–98% for prostate cancer [16,17,18,19,20,21,22], and 69–80% for heart disease [23,24]. …”

Section: Discussionsupporting

confidence: 89%

What Can Interest Tell Us about Uptake of Genetic Testing? Intention and Behavior amongst Smokers Related to Patients with Lung Cancer

Sanderson

O’Neill

Bastian

et al. 2009

Public Health Genomics

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Background: Much of the research examining psychosocial aspects of genetic testing has used hypothetical scenarios, based on the largely untested assumption that hypothetical genetic testing intentions are good proxies for behavior. We tested whether hypothetical interest predicts uptake of genetic testing and whether factors that predict interest also predict uptake. Methods: Participants (n = 116) were smokers and related to patients with lung cancer, who completed a telephone survey. Interest in genetic testing for lung cancer risk was indicated by responding ‘definitely would’ to a Likert-style question. Internet-delivered genetic testing for lung cancer risk was then offered. Uptake was indicated by requesting the test and receiving the result. Results: 63% of participants said they ‘definitely would’ take the genetic test; uptake was 38%. Participants who said they ‘definitely would’ take the test were more likely than others to take the offered test (45% vs. 26%, p = 0.035). Interest was associated with attitudes towards genetic testing and motivation to quit smoking. Uptake was associated with motivation, prior awareness of genetic testing, and daily Internet use. Conclusion: Hypothetical interest only modestly predicts uptake of genetic testing. Interest in genetic testing likely reflects generally positive attitudes that are not good predictors of the choices individuals subsequently make.

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Section: Discussionsupporting

confidence: 89%

What Can Interest Tell Us about Uptake of Genetic Testing? Intention and Behavior amongst Smokers Related to Patients with Lung Cancer

Sanderson

O’Neill

Bastian

et al. 2009

Public Health Genomics

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“…Furthermore, they were inclined to undergo screening and, when possible, genetic testing. In a recent investigation similar results were found in an American population [45]. Unfortunately, susceptibility for the development of HPC cannot be evaluated yet by means of a laboratory test.…”

Section: Screening For Hpcsupporting

confidence: 59%

Genetic Susceptibility to Prostate Cancer

Verhage

Kiemeney²

2000

European Urology

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“…When men are more informed about prostate cancer and the screening process, they are more likely to seek early screening and have less anxiety [57,63]. Studies show that men (regardless of their family history), are very interested in genetic testing, but should be aware of the risks and benefits for the testing and results before proceeding [56,61,72,73].…”

Section: Screening Barriersmentioning

confidence: 99%

Increased cancer risk for individuals with a family history of prostate cancer, colorectal cancer, and melanoma and their associated screening recommendations and practices

Noe

Schroy

Demierre

et al. 2007

Cancer Causes Control

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Prostate cancer, colorectal cancer, and melanoma are three malignancies that appear to have strong genetic components that can confer additional risk to family members. Screening tools, albeit controversial, are widely available to potentially aide in early diagnosis. Family members are now more attuned to the risks and benefits of cancer screening, thus, it is imperative that physicians understand the screening tools and how to interpret the information they provide. We reviewed the current literature regarding the cancer risks for individuals with a family history of prostate cancer, colon cancer, and melanoma, the current screening recommendations for family members, and actual screening practices of individuals with a family history of these malignancies. This review should serve as a guide for physicians and cancer control planners when advising their patients and the public regarding screening decisions.

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Men’s attitudes regarding genetic testing for hereditary prostate cancer risk

Cited by 35 publications

References 30 publications

What Can Interest Tell Us about Uptake of Genetic Testing? Intention and Behavior amongst Smokers Related to Patients with Lung Cancer

What Can Interest Tell Us about Uptake of Genetic Testing? Intention and Behavior amongst Smokers Related to Patients with Lung Cancer

Genetic Susceptibility to Prostate Cancer

Increased cancer risk for individuals with a family history of prostate cancer, colorectal cancer, and melanoma and their associated screening recommendations and practices

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