Méningite lymphocytaire : Listeria monocytogenes, une étiologie à ne pas négliger chez l'enfant immunocompétent

Flodrops, H.; Houdon, L.; Gérardin, Patrick; Mesnage, Renaud; Edmar, A.; Picot, S.; Leriche, B; Comoy, J

doi:10.1016/j.arcped.2005.07.011

Cited by 8 publications

(2 citation statements)

References 12 publications

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“… 5 Lee [ 19 ] 7 y, 0 m F Gram stain negative on day 1; Gram stain positive Cocci on day 3 WBC 1500/mm 3 (N 30%) ; Glu 25; Pr 117 Vancomycin + gentamicin+ ampicillin for unknown days - 10 days EVD Discharged after 61 days No sequelae 6 Platnaris [ 20 ] 0 y, 7 m M Gram stain negative on day 1; culture positive on day 3 WBC 2550/mm 3 (N 80%) ; Glu 53; Pr 128,5 Gentamicin 14 days+ Ampicillin 21 days. - 10 days EVD Discharged after 30 days No sequelae 7 Flodrops [ 21 ] 7 y, 0 m F Gram stain negative on day 1; Culture positive on day 11 WBC 160/mm 3 (N 5%) ; Glu 58; Pr 266 Vancomycin 8 days + amoxicillin 21 days - 11 days EVD Discharged after unknown days No sequelae 8 Ulloa-Gutierrez [ 22 ] 3 y, 6 m M Gram stain negative on day 1; Gram positive Cocci on day 3 WBC 755/mm 3 (N 95%); Glu 21; Pr 266 Ampicillin + gentamicin 1 day until death - 5 days EVD Death on day 4 9 Ulloa- Gutierrez [ 22 ] 6 y, 6 m M Gram stain positive Coccobacilli on day 1; Culture positive on day 5 WBC 800/mm 3 (N 60%); Glu 32; Pr 79 Ampicillin + gentamicin 3 days until death - 7 days EVD Death on day 7 10 Ulloa- Gutierrez [ 22 ] 10 y, 0 m F Negative Gram stain on day 1; Culture negative. Negative Gram stain on day 3; Culture positive on day 5 WBC 6000/mm 3 (N 80%); Glu 62; Pr 121 Meropenem 22 days + Amikacin 10 days + Rifampin 14 days - 8 days EVD Discharged after 28 days Upper left arm tremor and adiadoc...…”

Section: Discussionmentioning

confidence: 99%

Listeria meningitis complicated by hydrocephalus in an immunocompetent child: case report and review of the literature

et al. 2020

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Background Listeria monocytogenes is a Gram-positive bacteria transmitted to human by animal stools, contaminated water and food. In children, Listeria monocytogenes typically affects newborns and immunocompromised patients often leading to invasive syndromes including sepsis, brain abscesses, meningitis, meningoencephalitis and rhombencephalitis. In healthy and immunocompetent children, Listeria meningitis is rare, but can progress rapidly and may be associated with severe complications (hydrocephalus, ventriculitis, cranial nerves palsy and cerebrospinal abscesses) and high mortality rate. Case presentation We describe a very uncommon case of meningoencephalitis due to Listeria monocytogenes in a 11-month-old immunocompetent girl. Cerebrospinal fluid (CSF) culture was positive on the second day. Antibiotic therapy was promptly started but the disease was complicated by neurological deterioration and decompensated hydrocephalus. The child required a very demanding pediatric and neurosurgical management and was discharged after 40 days without major sequelae. Conclusion Listeria is difficult to isolate and it is not susceptible to first-line treatment for bacterial meningitis with extended-spectrum cephalosporins. Early recognition is therefore crucial for a positive outcome. Pediatricians have to perform close clinical monitoring of these children and be aware of possible complications. A review of all cases of Listeria meningitis complicated by hydrocephalus in healthy children has been performed, to provide an overview on clinical features, treatment options and outcome.

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Section: Discussionmentioning

confidence: 99%

Listeria meningitis complicated by hydrocephalus in an immunocompetent child: case report and review of the literature

et al. 2020

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“…Pediatric lymphocytic meningoencephalitis due to L. monocytogenes is a serious form of brain infection, even in immunocompetent childhood, especially when an important inflammatory syndrome appears. Most persons frequently ingest listeriae, but they are apparently resistant to infection (Meng and Doyle 1998;Flodrops et al 2005;Swaminathan et al 2007). The infective dose depends on the immunological status of the human host and characteristics of the organism such as its virulence factors.…”

Section: Listeria Monocytogenesmentioning

confidence: 98%