Meningitis neoplásica. Revisión de una serie hospitalaria

Mateos, A. Jiménez; Naranjo, Fernando; Hernández, A. González; Pi, Óscar Fabre; Nicolás, Santiago Díaz; Fernández, J.C. López

doi:10.1016/j.nrl.2010.07.020

Cited by 4 publications

(2 citation statements)

References 30 publications

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“…The presence of malignant cells in the CSF establish an accurate diagnosis of NM. NM presents with variable neurological manifestations such as headache, altered mental state, nausea, and vomiting [6,10,11]. In the present case, DDS, but not NM itself, was thought to be responsible for the symptoms, because her neurological abnormalities were observed only during hemodialysis.…”

Section: Discussionmentioning

confidence: 63%

Dialysis disequilibrium syndrome induced by neoplastic meningitis in a patient receiving maintenance hemodialysis

Tsuchida¹,

Takata²,

Ikarashi³

et al. 2013

BMC Nephrol

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BackgroundDialysis disequilibrium syndrome is characterized by neurological symptoms resulting from cerebral edema, which occurs as a consequence of hemodialysis. Dialysis disequilibrium syndrome most often occurs in patients who have just started hemodialysis, during hemodialysis, or soon after hemodialysis; although it may also occur in patients who are under maintenance hemodialysis with pre-existing neurological disease.Case presentationA 70-year-old woman, who had been receiving maintenance hemodialysis for one year, was diagnosed with ovarian cancer by ascites cytological examination. Two years later, she reported severe headache and nausea during hemodialysis and was diagnosed with dialysis disequilibrium syndrome. Although brain images revealed mild hydrocephalus without any mass lesions, poorly differentiated adenocarcinoma cells were detected in her cerebrospinal fluid. These findings indicated that DDS was induced by neoplastic meningitis due to ovarian cancer metastasis.ConclusionNeoplastic meningitis should be considered and excluded in hemodialysis patients with dialysis disequilibrium syndrome and malignancy by cytological examination of the cerebrospinal fluid even if cerebral imaging shows no obvious lesions. This is the first reported case of dialysis disequilibrium syndrome induced by neoplastic meningitis in a patient receiving maintenance hemodialysis.

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Section: Discussionmentioning

confidence: 63%

Dialysis disequilibrium syndrome induced by neoplastic meningitis in a patient receiving maintenance hemodialysis

Tsuchida¹,

Takata²,

Ikarashi³

et al. 2013

BMC Nephrol

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“…In lung cancer patients, metastases to the peritoneum as well as to the spinal space are rare (1–10). Carcinomatous meningitis, which attracts increasing attention as a recurrence site in patients who received treatment with epidermal growth factor receptor-tyrosine kinase inhibitors (EGFR-TKIs) (2–8), is a devastating event occurring in lung cancer patients (9–10) for which currently available treatment options are limited and the prognosis remains poor (1,9–10).…”

Section: Introductionmentioning

confidence: 99%

Peritoneal and meningeal relapse from lung adenocarcinoma after a response to gefitinib: A case report

Kurishima

Miyazaki

Tamura

et al. 2013

Molecular and Clinical Oncology

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The prognosis of carcinomatous peritonitis and meningitis is poor since ascites and focal neurological dysfunctions usually do not improve despite the available treatment options for this devastating disease. This is a case report of peritoneal and meningeal relapse from lung adenocarcinoma following a response to gefitinib. A 72-year-old woman was diagnosed with adenocarcinoma in the upper lobe of the left lung, accompanied by a massive carcinomatous pleural effusion. Following a cisplati-based chemotherapy, gefitinib was initiated, achieving satisfactory disease control. At 8 months after gefitinib initiation, the patient developed abdominal distension, gait disturbance and visual disorder of the right eye. Adenocarcinoma cells were detected in the ascitic and pleural fluids. The findings of this case report suggest that clinicians should remain vigilant for this type of metastasis, although it is rarely encountered.

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Meningitis neoplásica en tumores sólidos: revisión actualizada de diagnóstico, pronóstico, manejo terapéutico y direcciones futuras

Molina¹,

Penas‐Prado²

2022

Neurología

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Meningitis neoplásica. Revisión de una serie hospitalaria

Abstract: Neoplastic meningitis is a severe complication of both solid and haematological tumours. We stress the importance of maintaining a high level of suspicion to achieve early diagnosis, since the average survival probability for neoplastic meningitis patients is low.

Cited by 4 publications

References 30 publications

Dialysis disequilibrium syndrome induced by neoplastic meningitis in a patient receiving maintenance hemodialysis

Dialysis disequilibrium syndrome induced by neoplastic meningitis in a patient receiving maintenance hemodialysis

Peritoneal and meningeal relapse from lung adenocarcinoma after a response to gefitinib: A case report

Meningitis neoplásica en tumores sólidos: revisión actualizada de diagnóstico, pronóstico, manejo terapéutico y direcciones futuras

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