Méningo-vascularite bactérienne révélant un adénome hypophysaire

Bouchal, Siham; Razzouki, H.; Elkhyat, S.; Maâroufi, Mohamed; Ouali, O. El; Messouak, O.; Belahsen, M.F.

doi:10.11604/pamj.2015.20.7.5271

Cited by 4 publications

(3 citation statements)

References 12 publications

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“…Only one case of transient elevation of ACTH with hypercortisolemia associated with hyperprolactinemia was observed in our study[14]. On the other hand, we have underlined 4 cases of panhypopituitarism associated with hyperprolactinemia[1,5,9,10]. The panhypopituitarism would probably be secondary to a compression of the pituitary stem disconnecting the pituitary gland, which is a rare situation in the PM.Dopaminergic agonists (cabergoline or bromocriptine) represent the first choice treatment of macroprolactinomas without alteration of the ophthalmic examination (fundus examination and visual field).…”

mentioning

confidence: 46%

“…Moreover, the closure of the osteomeningeal breach is not systematic and should be performed only when the leakage of the CSF is important [1]. In our study, six patients had presented episodes of rhinorrhea before the diagnosis of BM, among which only 33.33% (2/6) had benefited a closure of the osteomeningeal breach [5,8].…”

Section: Doi : 1014302/issn2470-5020jnrt-17-1503mentioning

confidence: 81%

“…Ophthalmoplegia is the consequence of the invasion or compression of the oculomotor nerves in the cavernous sinus by the PM [9]. The disturbance of consciousness could also be a sign related to PM by endocrine disorders especially the lackness of corticotropic axis [1,5,9,10].…”

Section: Discussionmentioning

confidence: 99%

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Bacterial Meningitis Associated With Pituitary Macroadenoma: Systematic Review.

Daouda

Assadeck

Djibo

2017

JNRT

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Introduction -Bacterial meningitis complicates rarely pituitary macroadenomas. The aim of our systematic review is to study the features of the association between bacterial meningitis and pituitary macroadenoma.Methods -We conducted a literature search in both MedLine and Google Scholar database from 1967 to October 2016 and reviewed all cases described of the association between bacterial meningitis and pituitary macroadenoma apart from any surgical act and without pituitary apoplexy.Results -We found 14 articles describing 16 patients aged of 22-69 years old with a male predominance (sex ratio 4.3). Two patients (12.5%) had a well-documented clinical history of pituitary macroadenoma prior to the diagnosis of bacterial meningitis. Rhinorrhea has been found as the most common symptom through six patients (37.5%). Through the CSF culture, bacterial meningitis among patients suffering of pituitary macroadenoma commonly was due to Streptococcus pneumoniae. The examination in 18.75% of cases revealed signs related to pituitary macroadenoma (ophthalmoplegia and blindness). Six patients (37.5%) had received a treatment by dopaminergic agonist alone and 4 patients (25%) were treated with dopaminergic agonist associated with surgical treatment. Surgical treatment consisted of closure of the osteomeningeal breach in 12.5% (2/16) and tumor resection in 31.25% (5/16). Three patients (18.75%) had benefited tumor resection without prior agonist treatment. The mortality was 12.5% (2/16). Conclusion -Our systematic review shows that bacterial meningitis represents a rare initial symptom leading to the diagnosis of invasive pituitary macroadenoma.

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confidence: 46%

Section: Doi : 1014302/issn2470-5020jnrt-17-1503mentioning

confidence: 81%

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Bacterial Meningitis Associated With Pituitary Macroadenoma: Systematic Review.

Daouda

Assadeck

Djibo

2017

JNRT

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Une complication rare de macroadénome hypophysaire : méningite bactérienne

et al. 2015

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Pituitary Adenoma Complicated by Acute Bacterial Meningitis in a Patient in Kara (Togo)

Djalogue,

Agba,

Mossi

et al. 2023

OJIM

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Introduction: In the context of pituitary adenoma, bacterial meningitis is a possible complication of surgical or medical treatment. The occurrence of meningitis before any treatment is exceptional, explained by the existence of an osteomeningeal breach caused by the adenoma whose main symptom is rhinorrhea. Case Report: We report a case of bacterial meningitis complicating a prolactin pituitary macroadenoma. The patient had been referred for jet vomiting in a febrile context preceded by headaches and visual blurring. There was no rhinorrhea. The examination revealed a meningeal syndrome and the diagnosis of acute bacterial meningitis was made. The isolated germ was the pneumococcus. Faced with headaches and visual blurring, a cerebral scan revealed a pituitary macroadenoma and pituitary hormone dosage had shown hyperprolactinemia. The meningitis was sterilized and the prolactinoma was treated with dopaminergic agonists. This allowed the normalization of prolactinemia and the disappearance of symptoms. Conclusion: The pituitary adenoma was complicated by bacterial meningitis without treatment and the presence of a meningeal breach. Hormonal and bacterial treatments have been successful.

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Méningo-vascularite bactérienne révélant un adénome hypophysaire

Cited by 4 publications

References 12 publications

Bacterial Meningitis Associated With Pituitary Macroadenoma: Systematic Review.

Bacterial Meningitis Associated With Pituitary Macroadenoma: Systematic Review.

Une complication rare de macroadénome hypophysaire : méningite bactérienne

Pituitary Adenoma Complicated by Acute Bacterial Meningitis in a Patient in Kara (Togo)

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