Meniscal ossicles: Two case reports and a review of the literature

Liu, Stephen H.; Osti, Leonardo; Raskin, Alexander; Merlo, F.; Bocchi, L

doi:10.1016/s0749-8063(05)80115-x

Cited by 29 publications

(16 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Meniscal mineralization is a poorly understood condition that has been reported in reptiles, rodents, birds, nondomestic cats, and nonhuman primates. [1][2][3][4] Although described in people, it is considered a rare condition [5][6][7][8][9][10][11][12] and there have been a few case reports in dogs and domestic cats. 1,13,14 The cause of meniscal mineralization (meniscal ossification 1,2,[11][12][13][14][15] ; meniscal ossicles [6][7][8][9][10][11]16 ; meniscal calcification 1,5,13 ) is unknown.…”

mentioning

confidence: 99%

“…Developmental (phylogenetic) and posttraumatic causes have been suggested in people. 6,7,10,12 The phylogenetic theory suggests that meniscal mineralization represents a congenital vestigial structure that should be interpreted as a variant of normal anatomy. 6,7 The posttraumatic theory asserts that meniscal mineralization is acquired by degeneration or metaplasia after isolated or recurrent trauma.…”

mentioning

confidence: 99%

“…6,7,10,12 The phylogenetic theory suggests that meniscal mineralization represents a congenital vestigial structure that should be interpreted as a variant of normal anatomy. 6,7 The posttraumatic theory asserts that meniscal mineralization is acquired by degeneration or metaplasia after isolated or recurrent trauma. 7 It has been suggested that meniscal mineralization is a normal anatomic feature in nondomestic cats, 2 a primary vestigial anomaly in dogs and cats, 1,14 and to occur secondary to trauma or in association with cranial cruciate ligament rupture in dogs and cats.…”

mentioning

confidence: 99%

See 2 more Smart Citations

Meniscal Mineralization in Domestic Cats

et al. 2010

View full text Add to dashboard Cite

show abstract

mentioning

confidence: 99%

mentioning

confidence: 99%

mentioning

confidence: 99%

See 1 more Smart Citation

Meniscal Mineralization in Domestic Cats

et al. 2010

View full text Add to dashboard Cite

show abstract

“…Although the etiology of meniscal ossicle is still controversial, mucoid degeneration, 3,7) traumatic 8) and phylogenetic theories 3,7,9) have been proposed in the literature. In this case, preoperative MRI and arthroscopic examination during surgery did not reveal any bony defect or irregular surface that would have suggested avulsion fracture near the tibial insertion, and the ossicle was completely embedded in the posterior horn with no bone marrow exposure from the surface …”

Section: Discussionmentioning

confidence: 99%

“…3) Traditionally, arthroscopic resection of the ossicle is recommended for symptomatic cases. 4) However, some articles recommend arthroscopic resection and meniscal repair as adequate treatments.…”

mentioning

confidence: 99%

Meniscal Ossicle

Lee

Wang

Jung

2016

J Korean Orthop Assoc

View full text Add to dashboard Cite

Since the description of meniscal ossicle was introduced by WatsonJones and Roberts 1) in 1934, a number of authors have reported this rare abnormality. The prevalence of meniscal ossicle was found to be 0.15% among 1,287 consecutive knee magnetic resonance imaging (MRI) examinations.2) The most common site of meniscal ossicle is in the posterior horn of the medial meniscus.3) Traditionally, arthroscopic resection of the ossicle is recommended for symptomatic cases. 4) However, some articles recommend arthroscopic resection and meniscal repair as adequate treatments. 5,6) We performed arthroscopic meniscal resection including the ossicle and microfracture to treat meniscal ossicle and the cartilage lesion in the medial femoral condyle accompanied by medial meniscus posterior horn radial tear. This patient was diagnosed with meniscal ossicle of the knee based on the results of a histopathological biopsy. CASE REPORTA 48-year-old male was referred to our hospital for pain and intermittent locking symptoms in the right knee that had begun 6 months before. He was treated conservatively at a local clinic, but his symptoms did not improve. Physical examination at our hospital that an ossicle with an isointensity cortical rim was embedded within the posterior horn of the medial meniscus and that the posterior horn was detached from its tibial insertion (Fig. 1C, 1D).Arthroscopy was performed with 90-degree flexion of the right left knee. Probing in the arthroscopic view revealed a tear in the posterior horn of the medial meniscus at the tibial insertion. Integrity was partially maintained, but it was loose and unstable because of the degenerative changes in the soft tissue ( Fig. 2A). Meanwhile, although the normal meniscus lateral to the tear displayed swelling and a palpable solid mass inside, there were no lesions that suggested an avulsion fracture of the tibial insertion (Fig. 2B). In the meantime, the outerbridge classification grade IV cartilage defect on the medial femoral condyle was observed, likely caused by repeated contact with the enlarged hard posterior horn (Fig. 2C). Meniscectomy was performed accordingly for the posterior horn radial tear, and the mass embedded inside the meniscus was resected along with normal tissue because separate resection was impossible. Suture was not performed because probing after resection showed that reattachment of the residual meniscus to its normal anatomical location was impossible. Meanwhile, marrow stimulation by microfracture was performed for the cartilage lesion in the medial femoral condyle. The resected mass was sized 10×5×10 mm macroscopically and was surrounded by smooth, white cartilage (Fig. 3A). A histo- Meniscal ossicle of the knee, an ossified tissue formed within the meniscus, is rare in humans. We experienced a case of a 48-yearold male with no history of trauma, who presented with intermittent locking symptoms and knee pain upon standing. The patient was diagnosed with meniscal ossicle and cartilage lesion in the medial femoral condyle accompanied by ...

show abstract

Formation and maturation of the murine meniscus

2016

View full text Add to dashboard Cite

Meniscal injuries are commonplace, but current surgical repair procedures do not prevent degenerative joint changes that occur after meniscal injury and often lead to osteoarthritis. Successful tissue regeneration in adults often recapitulates events that occur during embryogenesis, suggesting that understanding the regulatory pathways controlling these early processes may provide clues for developing strategies for tissue repair. While the mouse is now widely used to study joint diseases, detailed knowledge of the basic biology of murine meniscus is not readily available. Here, we examine meniscal morphogenesis in mice from embryonic day 13.5 (E13.5) to 6 months of age using histology, in situ hybridization, and immunohistochemistry. We find that the meniscus is a morphologically distinct structure at E16 when it begins to regionalize. At birth, the meniscus has a distinguishable inner, avascular, round chondrocyte cell region, an outer, vascularized, fibroblast cell region, and a surface superficial zone. Maturation begins at 2 weeks of age when the meniscus expresses type I collagen, type II collagen, type X collagen, and MMP-13 in specific patterns. By 4 weeks of age, small areas of ossification are detected in the anterior meniscal horn, a common feature seen in rodents. Maturation appears complete at 8 weeks of age, when the meniscus resembles the adult structure complete with ossifying tissue that contains bone marrow like areas. Our results provide, the first systematic study of mouse meniscal development and will be a valuable tool for analyzing murine models of knee joint formation and disease. © 2016 Orthopaedic Research Society. Published by Wiley Periodicals, Inc. J Orthop Res 35:1683-1689, 2017.

show abstract

Meniscal ossicles: Two case reports and a review of the literature

Cited by 29 publications

References 5 publications

Meniscal Mineralization in Domestic Cats

Meniscal Mineralization in Domestic Cats

Meniscal Ossicle

Formation and maturation of the murine meniscus

Contact Info

Product

Resources

About