Menstrual blood loss with copper intrauterine devices

Hefnawi, F; Askalani, H; Zaki, K.

doi:10.1016/0010-7824(74)90026-2

Cited by 47 publications

(6 citation statements)

References 8 publications

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“…The usual medical treatments for menorrhagia are the combined oral contraceptives and in some countries antifibrinolytic agents which can achieve a 50% reduction in menstrual blood loss (Callender et al 1970;Nilsson & Rybo 1971;Hefnawi et al 1974;Kasonde & Bonnar 1975).…”

Section: Discussionmentioning

confidence: 99%

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Treatment of Menorrhagia with Intrauterine Release of Progesterone

Bergqvist¹,

Rybo²

1983

Obstetrical & Gynecological Survey

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In 12 women with menorrhagia Q 80 ml per menstrual period) a progesterone-releasing device (Progestasert) was inserted. The women were followed by repeated measurements of the blood loss for 12 periods. The menstrual blood loss was significantly reduced after 1 month but the duration of bleeding was somewhat prolonged. Twelve months after insertion the menstrual blood loss amounted to 35% of the blood loss before the insertion. The Progestasert is a valuable treatment for menorrhagia.

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Section: Discussionmentioning

confidence: 99%

“…Iron deficiency is seen in 2&25% of women of fertile age in developing countries (Rybo 1966;Hefnawi et al 1974) and it is also prevalent in developed countries (Hallberg 1970). Iron deficiency is seen in 2&25% of women of fertile age in developing countries (Rybo 1966;Hefnawi et al 1974) and it is also prevalent in developed countries (Hallberg 1970).…”

mentioning

confidence: 99%

Treatment of Menorrhagia with Intrauterine Release of Progesterone

Bergqvist¹,

Rybo²

1983

Obstetrical & Gynecological Survey

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show abstract

Section: Discussionmentioning

confidence: 99%

“…The problem of iron deficiency is worldwide. Iron deficiency is seen in 2&25% of women of fertile age in developing countries (Rybo 1966;Hefnawi et al 1974) and it is also prevalent in developed countries (Hallberg 1970). Excessive menstrual blood loss is the most common cause of iron deficiency in women.…”

mentioning

confidence: 99%

Treatment of menorrhagia with intrauterine release of progesterone

Bergqvist¹,

Rybo

1983

BJOG

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“…In a previous study, quantitative estimation of menstrual blood loss before and after insertion of the Lippes Loop has shown that the blood loss was almost doubled after insertion (9). In developing countries the incidence of iron deficiency anemia is high; hence, the increased blood loss is a serious problem.…”

Section: Women Wearing Lippes Loops and Cu-t(200)smentioning

confidence: 99%

Fibrinolytic Activity of Menstrual Blood in Normal and Menorrhagic Women and in Women Wearing the Lippes Loop and the Cu‐T(200)

Hefnawi

Kandil

et al. 1979

Intl J Gynecology & Obste

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Assessment was made of the fibrinolytic activity in menstrual and peripheral blood of 30 normally menstruating and 30 menorrhagic patients and of 30 women wearing Lippes Loops and 15 wearing CU-T (200)s. Assessment was performed by measuring the area of lysis on heated and unheated fibrin plates. Also, histochemical identification of fibrin fibrils in the menstrual endometrium was performed by Mallory's phosphotungstic acid hematoxylin method. Results in the normally menstruating group were compared to those of the menorrhagic women, and together these were compared with results in the groups of women wearing intrauterine devices. The fibrinolytic activity in menstrual blood was significantly increased in menorrhagic patients compared to that in normally menstruating patients, but no significant difference was detected in the plasma of either group. The histochemical study of the normally menstruating endometrium revealed dense intravascular and extravascular deposits of fibrin. Less dense intravascular fibrin deposits, but no extravascular ones, were present in the menorrhagic patients. The increase in the fibrinolytic activity of menstrual blood and the decrease in the density of fibrin deposits in the menstrual endometrium of the menorrhagic women were thus associated and were probably involved in the excessive menstrual loss. The fibrinolytic activity of menstrual blood in women wearing Lippes Loops was higher than that in women with Cu-T (200)s and was associated with decreased density of fibrin fibrils in the menstruating endometrium. This may explain the increased blood loss associated with the use of the Lippes Loop.

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Menstrual blood loss with copper intrauterine devices

Cited by 47 publications

References 8 publications

Treatment of Menorrhagia with Intrauterine Release of Progesterone

Treatment of Menorrhagia with Intrauterine Release of Progesterone

Treatment of menorrhagia with intrauterine release of progesterone

Fibrinolytic Activity of Menstrual Blood in Normal and Menorrhagic Women and in Women Wearing the Lippes Loop and the Cu‐T(200)

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