Mental and physical fatigue-related biochemical alterations

Nozaki, Satoshi; Tanaka, Masaaki; Mizuno, Kei; Ataka, Suzuka; Mizuma, Hiroshi; Tahara, Tsuyoshi; Sugino, Tomohiro; Shirai, Toshizumi; Eguchi, Akiyo; Okuyama, Kaori; Yoshida, Kaoru; Kajimoto, Yoshitaka; Kuratsune, Hirohiko; Kajimoto, Osami; Watanabe, Yasuyoshi

doi:10.1016/j.nut.2008.07.010

Cited by 73 publications

(56 citation statements)

References 32 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Mental and physical fatigue can alter some biochemical parameters, like serum triglyceride (TG), free fatty acid (FFA) and cortisol (Nozaki et al, 2009). Imposing restraint stress on mice can result in tiredness and a poor utilization of TG, along with a decrease in lipoprotein lipase (LPL) activity in omental adipose tissue (Kurihara et al, 2006).…”

Section: Introductionmentioning

confidence: 99%

Phloridzin improves lipoprotein lipase activity in stress-loaded miceviaAMPK phosphorylation

Wang

et al. 2014

International Journal of Food Sciences and Nutrition

View full text Add to dashboard Cite

Long-term stress exposure can lead to disturbed homeostasis and cause many life-style diseases. Phloridzin possesses various bioactivities, but the understanding of the effects of phloridzin on stress-related lipid metabolism disorder is limited. Our results demonstrate that phloridzin improved plasma lipoprotein lipase (LPL) activity and triglyceride metabolism in restrained mice. A decrease of angiopoietin-like protein 4 (ANGPTL4) mRNA expression and an increase of AMP-activated protein kinase (AMPK) phosphorylation were observed after phloridzin treatment. After inhibiting AMPK phosphorylation, the effects of phloridzin on the amelioration of plasma LPL activity and suppression of ANGPTL4 expression were blocked. In addition, cardiac AMPK phosphorylation, plasma LPL activity and ANGPTL4 expression were also affected by phloridzin, even if the glucocorticoid receptor was blocked. Taken together, the down-regulation of ANGPTL4 expression by phloridzin was probably via a direct activation of AMPK pathway. This discovery can provide a biochemical and nutritional basis for the use of phloridzin-containing food and beverage in daily life.

show abstract

Section: Introductionmentioning

confidence: 99%

Phloridzin improves lipoprotein lipase activity in stress-loaded miceviaAMPK phosphorylation

Wang

et al. 2014

International Journal of Food Sciences and Nutrition

View full text Add to dashboard Cite

show abstract

“…Insufficient oxygen causes hypoxia and inhibits aerobic metabolism, which undermines the exercise capacity. The large amount of hemoglobin in erythrocytes acts as buffer and carries carbon dioxide and oxygen; thus, the hemoglobin content affects the exercise capacity (Xu and Luo 2001;Nozaki et al 2009). The hemoglobin content in mice was measured after 30 days of intragastric administration.…”

Section: Effects Of Anti-exercise-fatiguementioning

confidence: 99%

Antioxidant activity and anti-exercise-fatigue effect of highly denatured soybean meal hydrolysate prepared using neutrase

2013

J Food Sci Technol

View full text Add to dashboard Cite

Highly denatured soybean meal is a by-product of soybean oil extraction obtained through high-temperature desolventization. High-temperature treatment can result in soybean protein denaturation. Compare with ordinary soybean meal, the protein structure of highly denatured soybean meal has changed. Highly denatured soybean meal was pretreated with thermal treatment or ultrasonication, and then hydrolyzed with neutrase. The ultrasonicated hydrolysate exhibited better antioxidant activity than the thermally treated hydrolysate. The ultrasonication increased 1,1-diphenyl-2-pycryl hydrazyl (DPPH) radical scavenging activity by 8.31 % and reduction capacity by 10.19 %. The highly denatured soybean meal hydrolysate ultrasonicated at 400 W exhibited the highest antioxidant activity. The DPPH radical scavenging activity was 56.22 % and reduction capacity was 0.717. The ultrasonicated hydrolysate at 400 W was fractionated using ultrafiltration into three fractions: I (>10 kDa), II (5 kDa to 10 kDa), and III (<5 kDa). The in vitro antioxidant activity and others in vivo anti-exercise-fatigue effect of the three fractions (I, II, and III) were determined. Fraction III exhibited the highest DPPH radical scavenging activity and reduction capacity, improved the hemoglobin and hepatic glycogen content and reduced blood urea nitrogen and blood lactic acid. Fraction III improved the activity of superoxide dismutase (SOD) and glutathione peroxidase (GSH-PX) and reduced the malonaldehyde (MDA) content in mouse livers. Therefore, the highly denatured soybean meal hydrolysate has an anti-oxidative effect and it significantly alleviates exercisefatigue in mice. Amino acids of hydrolysate were determined.Results showed that the antioxidant activity and anti-exercisefatigue effect were related to the amino acid compositions.

show abstract

“…Also, like salivary α-amylase, the salivary cortisol is known to have circadian rhythm, with a high concentration in the morning which decreases rapidly by midday, so it is essential to perform evaluations by comparing the results with a control sample. Salivary cortisol responds to both physical and psychological stress (Nozaki et al, 2009), and it has been shown that the abovementioned massage chair reduced cortisol concentrations caused by psychological stress loading. Furthermore, as introduced in this section, it is also used to evaluate the stress of surgeons when using a laparoscope robot.…”

Section: Fig 2 Physiological Reaction To Stress Loadingmentioning

confidence: 99%

Method for Objectively Evaluating Psychological Stress Resulting when Humans Interact with Robots

Taniguchi¹,

Nishikawa²,

Sugino³

et al. 2009

Advances in Human-Robot Interaction

Self Cite

View full text Add to dashboard Cite

Mental and physical fatigue-related biochemical alterations

Cited by 73 publications

References 32 publications

Phloridzin improves lipoprotein lipase activity in stress-loaded miceviaAMPK phosphorylation

Phloridzin improves lipoprotein lipase activity in stress-loaded miceviaAMPK phosphorylation

Antioxidant activity and anti-exercise-fatigue effect of highly denatured soybean meal hydrolysate prepared using neutrase

Method for Objectively Evaluating Psychological Stress Resulting when Humans Interact with Robots

Contact Info

Product

Resources

About