INCE Sakel (10) introduced Insulin Shock Treatment (hereafter called 1ST) as a specific treatment for schizophrenia more than ten years ago, there has been considerable speculation and research as to its effect on the psychiatric and psychological condition of patients. Though there have been numerous statistical studies on remission rates following 1ST, there is little agreement. For example, Salzman (n) and Hinko and Lipschutz (6) in recent studies report that remissions are as frequent and as stable in untreated patients as in patients given 1ST. In contrast, Kalinowsky and Hoch (7) conclude, after a survey of the literature, that 1ST results in significantly higher remission rates. Much of the lack of agreement is, of course, attributable to the difficulty in comparing remission rates and similarity of treatment in different hospitals. Diagnostic principles, type of patients selected for treatment, intensity of treatment, criteria for evaluation of treatment, etc., may also vary significantly from hospital to hospital. In an effort to obtain more objective evidence as to the effect of 1ST and to provide prognostic cri-