Mental health disorders and readmissions following acute myocardial infarction in the United States

Abstract

Hospital readmissions following an acute myocardial infarction (MI) are associated with increased mortality and morbidity. The aim of this study was to investigate if there is a significant association between specific mental health disorders (MHD) and risk of hospital readmission after an index hospitalization for acute MI. We analyzed the U.S. National Readmission Database for adult acute MI hospitalizations from 2016 to 2017. Co-morbid diagnoses of MHD were obtained using appropriate ICD-10-CM diagnostic codes. The primary outcome of interest was 30-day all-cause unplanned readmission. Cox-regression analysis was used to identify the association of various MHD and risk of 30-day readmission adjusted for demographics, medical and cardiac comorbidities, and coronary revascularization. We identified a total of 1,045,752 hospitalizations for acute MI; patients had mean age of 67 ± 13 years with 37.6% female. The prevalence of any MHD was 15.0 ± 0.9%. After adjusting for potential confounders, comorbid diagnosis of major depression [HR 1.11 (95% CI 1.07–1.15)], bipolar disorders [1.32 (1.19–1.45)], anxiety disorders [1.09 (1.05–1.13)] and schizophrenia/other psychotic disorders [1.56 (1.43–1.69)] were independently associated with higher risk of 30-day readmission compared to those with no comorbid MHD. We conclude that MHD are significantly associated with a higher independent risk of 30-day all-cause hospital readmissions among acute MI hospitalizations.

Construction and validation of a predictive model for prolonged length of stay after PCI for patients with acute myocardial infarction.

“…Previous studies have indicated a correlation between longer hospital stays and a history of conditions such as diabetes and stroke [20] , as well as depression. Although the mechanisms remain unclear, there is also research suggesting that patient compliance with medical advice, medication adherence, and lifestyle habits are associated with longer hospital stays [21] . Therefore, future research should incorporate patients' social and psychological characteristics.…”

High Salt Intake Induces Active Coping Behaviors by Enhancing the Resilience against Psychological Stress in Mice

“…The role of salt intake in psychiatric disease remains controversial. Because patients with cardiovascular disease often have mental illnesses such as major depressive symptom [52,53], high salt intake has been suggested to be a risk factor for psychiatric diseases [6,8]. In contrast, it has been reported that low daily salt intake is a significant risk factor for mental distress [10] and that higher intake may protect people from depression [11,54].…”

A Relevância Da Limpeza Hospitalar No Combate a Infecção Cruzada

“…Não obstante, Sreenivasan et al (2022), descobriram um dos impactos de pacientes com depressão grave, transtornos bipolares e transtornos de ansiedade nas reiterações hospitalares após IAM. Estes indivíduos estão propensos a receber menos revascularização coronariana no período de internação por IAM e apresentam um risco independente significativamente aumentado para a reinternação no intervalo de 30 dias, destacando a ligação entre saúde mental e saúde cardiovascular.…”